نتایج جستجو برای: chemotypes
تعداد نتایج: 676 فیلتر نتایج به سال:
Cyanobacterial oligopeptides comprise a wide range of bioactive and/or toxic compounds. While current research is strongly focused on exploring new oligopeptide variants and their bioactive properties, the biological role of these compounds remains elusive. Oligopeptides production abilities show a remarkably patchy distribution among conspecific strains. This observation has prompted alternati...
In an effort to expand the stereochemical and structural complexity of chemical libraries used in drug discovery, the Center for Chemical Methodology and Library Development at Boston University has established an infrastructure to translate methodologies accessing diverse chemotypes into arrayed libraries for biological evaluation. In a collaborative effort, the NIH Chemical Genomics Center de...
Unlike other studies that only determined the chemical composition of essential oils depending on their geographic origin, this research investigated effect weather conditions (temperature, precipitation, and insolation) Nepeta nuda L. oil. The collection wild-growing N. was carried out during three successive years, 2019, 2020, 2021 at Rtanj Mountain (Serbia) same date (July 7th). Essential oi...
BACKGROUND: The medicinal plant of Thymus serpyllum L. in nature, depending on the geographical region, climatic conditions, and growing environment, is represented with some chemotypes. Composition quantitative content basic groups biologically active substances can be differed, thus their biological properties are also various.
 AIM: aim study was to determine possibility using ultrasoni...
The COVID-19 pandemic has forced scientists all over the world to focus their effort on searching for targeted drugs coronavirus chemotherapy. present review is an attempt systematize low-molecular-weight compounds, including well-known pharmaceuticals and natural substances that have exhibited high anti-coronavirus activity, not in terms of action targets, but structural type.
A number of inhibitors of the essential Mycobacterium tuberculosis mycolic acid transporter, MmpL3, are currently under development as potential novel antituberculosis agents. Using the checkerboard method to study the interaction profiles of various antituberculosis drugs or experimental compounds with two different chemotypes inhibiting this transporter (indolcarboxamides and adamantyl ureas)...
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