To investigate whether antecedent cytomegalovirus (CMV) infections in patients with Guillain-Barré syndrome are associated with the presence of specific antiganglioside antibodies, acute phase serum samples from 130 patients with Guillain-Barré syndrome and 200 controls were tested. Anti-GM2 IgM antibodies were found more often in patients with Guillain-Barré syndrome with CMV infection (22%) t...

Guillain-Barré is one of the most common syndromes causing acute flaccid paralysis worldwide, usually starting with a motor component and spreading upwards; organism this pathology Campylobacter Jejuni. However, due to pandemic, presence neurological has been reported in patients SARS-CoV2. The process by which disease produced interaction between immunological processes activation autoantibodi...

INTRODUCTION Guillain-Barré syndrome is an acute demyelinating disorder of the peripheral nervous system that results from an aberrant immune response directed at peripheral nerves. Autonomic abnormalities in Guillain-Barré syndrome are usually transient and reversible. We present a case of Guillain-Barré syndrome requiring a permanent pacemaker in view of persistent symptomatic bradyarrhythmia...

Molecular mimicry between self and microbial components has been proposed as the pathogenic mechanism of autoimmune diseases, and this hypothesis is proven in Guillain-Barré syndrome. Guillain-Barré syndrome, the most frequent cause of acute neuromuscular paralysis, sometimes occurs after Campylobacter jejuni enteritis. Gangliosides are predominantly cell-surface glycolipids highly expressed in...

Guillain-Barre syndrome, an acute or subacute inflammatory demyelinating polyradiculoneuropathy, usually causes ascending paralysis, areflexia, and sensory disturbances. l A similar syndrome, more chronic and sometimes relapsing, has been called chronic inflammatory demyelinating polyneuropathy.2 Thought to have an immunologic cause, Guillain-Barre syndrome can be found in association with infe...

Guillain-Barn! syndrome is a subacute inflammatory demyelinating polyradicular neuropathy of the peripheral nerves. It is characterized by varying degrees of weakness, sensory abnormalities, and autonomic dysfunction. The cause of Guillain-Barre syndrome is not completely understood, but it is believed to be a postinfectious autoimmune disorder, because approximately two thirds of all cases are...

BACKGROUND Acute flaccid paralysis (AFP) can be caused by a number of conditions. A common preventable cause is poliomyelitis which is still being reported in Pakistan, Guillain Barre Syndrome (GBS), also known as Acute Inflammatory Demyelinating Polyneuropathy, is another common cause of acute flaccid paralysis. It is important to recognize GBS in childhood as parents consider all acute flacci...

Miller-Fisher syndrome (MFS) is an extremely rare, autoimmune, axonal polyradiculoneuropathy which takes place during childhood. It is characterised by the clinical triad of ataxia, ophthalmoplegia and arreflexia. The annual incidence of Miller-Fisher syndrome is 0.09 cases per 100 000 inhabitants. The few published series that exist with children account for approximately 9% of the total of ac...

Guillain Barre Syndrome (GBS), was originally described by Guillain et. al in 1916 following two case reports. In 1936 Guillain himself described more cases in a further report} and since then this condition has been widely published. Several different terms have been used to describe this illness and these includes acute infective polyneuritis, acute febrile polyneuritis of OsIer and acute idi...

Thirteen cases of the Guillain-Barré syndrome are reviewed, all occurring with a similar relationship to recent commencement of treatment with the antidepressive drug zimeldine. The risk of developing Guillain-Barré syndrome was increased about 25-fold among patients receiving zimeldine, as compared with the natural incidence of the disorder. The cases described provide strong evidence that Gui...