bone marrow specimens from leukemic patients were studied in a 5 year period beginning in 1982 in children's medical center of teheran,a teaching and referral center for pediatric medicine. the slides were stained by giemsa-wright stains, read by at least two persons experienced in bone marrow pathology and classified according to f.a.b. recommendations. peroxidase or sudan black-b and p.a...

OBJECTIVE We conducted a systematic review and meta-analysis of previous observational epidemiologic studies examining the relationship between residential pesticide exposures during critical exposure time windows (preconception, pregnancy, and childhood) and childhood leukemia. DATA SOURCES Searches of MEDLINE and other electronic databases were performed (1950-2009). Reports were included i...

ISSN 0931-4288 No. 626-627, Feb. 7, 2013 www.strahlentelex.de English version Increased leukemia rates in children from Belarus after Chernobyl Alfred Körblein [email protected] February 2013 A trend analysis of data from Belarus finds a statistically significant 33% increase in the incidence of leukemia in children in 1987, following the Chernobyl nuclear disaster in 1986 (RR=1.33; P=0.0...

Evidence has emerged that childhood leukemia is initiated in utero. High birth weight is one of the few birth-related factors that has been associated with childhood leukemia, albeit not consistently. The authors conducted a meta-analysis of studies of the association between birth weight and childhood leukemia risk. Study-specific odds ratios for leukemia were calculated, using a cutoff at 4,0...

All populations are exposed to varying degrees of electromagnetic fields (EMF); in this study we consider only extremely low frequency (ELF) and radio frequency (RF) fields. After the first study of ELF and childhood leukemia in 1979, intensive epidemiologic investigation has sought to shed light on the potential relation between EMF and childhood leukemia. Consistent associations from epidemio...

Although overall incidence is rare, leukemia is the most common type of childhood cancer. It accounts for 30% of all cancers diagnosed in children younger than 15 years. Within this population, acute lymphocytic leukemia (ALL) occurs approximately five times more frequently than acute myelogenous leukemia (AML) and accounts for approximately 78% of all childhood leukemia diagnoses. Epidemiologi...

BACKGROUND Leukemia is the most prevalent childhood cancer, and Acute Lymphoblastic Leukemia (ALL) constitutes 75% of all cases. Some epidemiological studies have shown a relationship between socioeconomic status (SES) and some childhood cancers. In the present study, an attempt was made to assess socioeconomical status in a case-control study. MATERIALS AND METHODS In 2010, a case-control st...

BACKGROUND While many studies have concluded that local traffic density is positively associated with childhood leukemia, the results are inconsistent. We therefore performed a meta-analysis to assess the relationship between traffic density and the risk of childhood leukemia. METHODS A systematic literature review was carried out using PubMed, EMBASE, and the Cochrane Library from January 19...

Although childhood acute lymphoblastic leukemia is the most common pediatric cancer, its etiology remains poorly understood. In an attempt to replicate the findings of 2 recent genome-wide association studies in a French-Canadian cohort, we confirmed the association of 5 SNPs [rs7073837 (P=4.2 x 10(-4)), rs10994982 (P=3.8 x 10(-4)), rs10740055 (P=1.6 x 10(-5)), rs10821936 (P=1.7 x 10(-7)) and r...