Since late 1980s four systems of stages of higher education and qualifications have been in force in Estonia. The higher education system has been changed or reorganized through three phases of reforms, important periods were in 1989-1991, 1995-1996 and 20012002. The latter phase of reforms was clearly facilitated and conducted by the progressive Bologna process. Similarly to other CEE countrie...

In this paper we discuss the new demands put on university faculty for involvement in delivery of Continuing Engineering Education. CEE programmes are often composed in the same way as on-campus programmes – which means straight forward for teachers to conduct. However, the needs for new knowledge and new competencies in small and medium sized enterprises and for teams in larger enterprises are...

We have previously shown that vanadium bromoperoxidase from Ascophyllum nodosum mediates production of the (R)-enantiomer of methyl phenyl sulfoxide with 91% enantiomeric excess. Investigation of the intrinsic selectivity of vanadium bromoperoxidase reveals that the enzyme catalyzes the sulfoxidation of methyl phenyl sulfide in a purely enantioselective manner. The K(m) of the enzyme for methyl...

Ligand Hsal-his (I) derived from salicylaldehyde and histamine has been covalently bound to chloromethylated polystyrene cross-linked with 5% divinylbenzene. Upon treatment with [VO(acac)(2)] in DMF, the polystyrene-bound ligand (abbreviated as PS-Hsal-his, II) gave the stable polystyrene-bound oxidovanadium(iv) complex PS-[V(IV)O(sal-his)(acac)] , which upon oxidation yielded the dioxidovanadi...

O6-Ethylthioethyldeoxyguanosine has been synthesized from 6-chloro-3',5'-di-O-acetyldeoxyguanosine and characterized by UV, fluorescence, and mass spectrometry. High-pressure liquid chromatography studies have shown that this modified nucleoside is formed when the one-armed sulfur mustard, chloroethyl ethyl sulfide, reacts with deoxyguanosine. This result supports the hypothesis that the mutage...

The development of new anticancer agents with lower toxicity, higher therapeutic index, and weaker tendency to induce resistant phenotypes in tumor cells is a continuous challenge for the scientific community. Toward that end, we showed previously that a new class of soft alkylating agents designed as phenyl-3-(2-chloroethyl)ureas (CEUs) inhibits tumor cell growth in vitro and that their effici...

The title compound, C19H17PS2, results from the direct deprotonation of di-phenyl-methyl-phosphine sulfide and subsequent reaction with diphenyl di-sulfide. The C-P and C-S bond lengths of 1.8242 (18) and 1.8009 (18) Å, respectively, of the central P-C-S linkage are comparable to those found in the sulfonyl analogue, but are considerably longer than those reported for the dimetallated sulfonyl ...