Pregnant dogs are susceptible to chloroform administered shortly before delivery or during labor, and show the same degree of liver injury as normal dogs, or even a somewhat greater one. Chloroform anesthesia may cause more or less hyaline necrosis in the border zone between the maternal and fetal parts of the placenta that may lead to hemorrhage, placental separation, and premature delivery. C...

Force fields based on a Lennard-Jones (LJ) 12-6 plus point charge functional form are developed for acetone and chloroform specifically to reproduce the minimum pressure azeotropy found experimentally in this system. Point charges are determined from a CHELPG population analysis performed on an acetone-chloroform dimer. The required electrostatic surface for this dimer is determined from ab ini...

Chloroform was discovered in 1831 by a French chemist, Soubeiran, and independently by the American, Samuel Guthrie of Sachett's Harbour, in the State ofNew York (Duncum, 1947). Soubeiran obtained impure chloroform, which he provisionally called " bichloric ether ", by distilling a mixture of chloride of lime and alcohol. Liebig, in the following year, obtained a purer chloroform, which he name...