The interrelationship of the requirement of choline, methionine, betaine, vitamin B12, and folic acid has been the subject of many recent investigations (2-5). That vitamin Blz functions in the intermediary metabolism of l-carbon units is also well recognized (1, 6-20, 21). However, while there have been several reports concerning the effect of the vitamin in viva and in vitro systems, the prec...

The interrelationship of the requirement of choline, methionine, betaine, vitamin B12, and folic acid has been the subject of many recent investigations (2-5). That vitamin Blz functions in the intermediary metabolism of l-carbon units is also well recognized (1, 6-20, 21). However, while there have been several reports concerning the effect of the vitamin in viva and in vitro systems, the prec...

BACKGROUND The repeatability of a risk factor measurement affects the ability to accurately ascertain its association with a specific outcome. Choline is involved in methylation of homocysteine, a putative risk factor for cardiovascular disease, to methionine through a betaine-dependent pathway (one-carbon metabolism). It is unknown whether dietary intake of choline meets the recommended Adequa...

Cholinergic neurotransmission supports motor, autonomic, and cognitive function and is compromised in myasthenias, cardiovascular diseases, and neurodegenerative disorders. Presynaptic uptake of choline via the sodium-dependent, hemicholinium-3-sensitive choline transporter (CHT) is believed to sustain acetylcholine (ACh) synthesis and release. Analysis of this hypothesis in vivo is limited in ...

two hundred and forty hubbard classic broiler chicks were used in a 35 day trial at chittagong veterinary and animal science university farm, bangladesh to study the effects of supplemental choline chloride on performance parameters, carcass characteristics and their association in commercial broiler. all birds had free access to ad libitum feeding. birds were fed four types of diet i.e. diet w...

In the accompanying paper (1) it is reported that rats maintained on a diet rnargiI~ in lipotropic activity developed fatty infiltration and fibrosis of the liver when given 15 per cent alcohol in lieu of drinking water or an isocaloric equivalent of sucrose over a period of 7 months. Since the hepatic changes could be prevented by supplementing the diet with choline or methionine, the possibil...

Two hundred and forty Hubbard Classic broiler chicks were used in a 35 day trial at Chittagong Veterinary and Animal Science University farm, Bangladesh to study the effects of supplemental choline chloride on performance parameters, carcass characteristics and their association in commercial broiler. All birds had free access to ad libitum feeding. Birds were fed four types of diet i.e. diet w...

Since, choline chloride caking causes serious operating difficulties and customer complaints, two experiments were conducted to optimize in vitro production of a novel encapsulated choline chloride (ECC) with minimum hygroscopic property and optimize delivery in gastrointestinal tract (GIT). The in vivo verification test of ECC was used to compare it with the commercial choline chloride (CC) in...

the construction and performance of an amperometric microbiosensor for the determination of choline chloride by immobilizing choline oxidase on a cellulose acetate membrane are described. the procedure of choline determination involved the electrochemical detection of enzymatically generated hydrogen peroxide. this microsensor has a linear response between 0.038-0.1 mm choline chloride. the res...