Acute and chronic inflammatory demyelinating polyneuropathies represent an important group of disorders. Although the acute form is more common, all clinical neurologists will eventually encounter patients with these disorders. Acute inflammatory demyelinating polyneuropathy, or Guillain-Barré syndrome, is the most common cause of acute generalized weakness. Chronic inflammatory demyelinating p...

Background and objective C-reactive protein is a pentameric protein which is generated in the liver and secreted in the blood to play a central role in inflammation. The measurement of C-reactive protein in the blood provides a reliable marker of chronic inflammation caused by infectious and other inflammatory agents. Increased levels of C-reactive protein have been associated with chronic infe...

background : this study aimed to investigate the association of seven common inflammatory diseases with type 2 diabetes (t2d) in the chinese mainland population. methods : participants were recruited from a great swathe of mainland from 2009 to 2013 for the cohort study. the demographic characteristics between patients with t2d or with inflammatory diseases, including age, sex, smoking status, ...

Sporadic inclusion body myositis (IBM) is the most common idiopathic inflammatory myopathy (IIM) after age 50 years. It presents with chronic insidious proximal leg and distal arm asymmetric muscle weakness. Despite similarities with polymyositis (PM), it is likely that IBM is primarily a degenerative disorder rather than inflammatory muscle disease. IBM is associated with a modest degree of cr...

Chronic rhinosinusitis is a common disorder of chronic inflammation of the upper respiratory tract. It is associated with significant symptoms and impairment of the quality of life of sufferers. Despite recent advances in the medical and surgical management of chronic rhinosinusitis, there remains a population of patients who fail to obtain relief from their symptoms. Chronic inflammation of th...

BACKGROUND Chronic inflammatory demyelinating polyradiculoneuropathy is a rare acquired immune-mediated progressive or relapsing disorder causing peripheral neuropathic disease of duration more than two months. Many individuals with chronic inflammatory demyelinating polyradiculoneuropathy fail to make a long-term recovery with current treatment regimes. The aim of this study was to prospective...

Crohn’s disease (CD) is a chronic, relapsing disorder belonging to inflammatory bowel diseases (IBD). It manifested by transmural inflammation found in any segment of the gastrointestinal tract. Chronic fatigue common and underrecognized symptom CD for which prevalence much higher population patients compared healthy population. stems from an intricate web interactions between various risk fact...

Introduction Pediatric chronic nonbacterial osteomyelitis (CNO) is a sterile inflammatory bone disorder in which innate and adaptive immunity dysfunction involved. Unifocal and multifocal disease courses are known. The modern treatment modalities include non-steroid anti-inflammatory drugs (NSAIDs), steroids, sulfasalazine (SSZ), methotrexate (MTX), bisphosphonates and biologic drugs TNFa and I...

Asthma is currently recognized as a chronic inflammatory disorder of the airways that leads to tissue injury and subsequent structural changes collectively called airway remodeling. Transgenic modeling of inflammatory mediators allows for the discovery of unexpected effects, dissection of downstream signaling events, and clues to future therapies.

background :attention deficit hyperactivity disorder (adhd) is the most common childhood neurological disorder. this disorder is more prevalent in some chronic diseases. the aim of this study was to investigate adhd in children with early stages of chronic kidney disease (ckd) and to compare it with healthy children.   methods : seventy five 5-16-year-old children with early stages of ckd (stag...