Chronic insomnia afflicts up to 10% of the population in Western industrialized countries. It is characterized by delayed sleep onset, problems in maintaining sleep, early morning awakening or the feeling of non-restorative sleep coupled with significant daytime impairments on an emotional, social or professional level. It can occur as a co-morbid condition in any other medical or mental disord...

Until recently, the association of chronic insomnia with significant medical morbidity was not established and its diagnosis was based solely on subjective complaints. We present evidence that insomnia with objective short sleep duration is the most biologically severe phenotype of the disorder, as it is associated with cognitive-emotional and cortical arousal, activation of both limbs of the s...

BACKGROUND Insomnia symptoms are common in the population and have negative psychosocial and functional sequelae. There are no prospective studies of the course of such symptoms and their impact, if any, in stroke survivors. This prospective cohort study investigated insomnia after stroke in working-age adults and evaluated its impact on psychological and functional outcomes over the subsequent...

Insomnia is a highly prevalent sleep disorder that frequently occurs in its acute form and occurs at a rate of approximately 10 per cent in its chronic form in many countries. There is a high prevalence of insomnia in a variety of medical and psychiatric conditions for which insomnia often serves as a risk factor. The aetiology and pathophysiology of insomnia is such that several factors may pr...

Copyright: © 2014 Álamo C, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Insomnia is the most common sleep disorder and approximately 10% of the world’s population will report that they suffer from ch...

The daytime consequences and correlates of insomnia were examined in the National Sleep Foundation and the Gallup Organization survey of 1,000 randomly selected Americans. Respondents were grouped as having occasional insomnia, chronic insomnia or no insomnia. There were dramatic differences in reported waking behaviors and psychosocial measures by insomniacs compared to those who do not report...

BACKGROUND To investigate the association between primary insomnia and dementia using a Taiwanese population-based database. METHODS This case-control study involved a subset of Taiwan's National Health Insurance Research Database of reimbursement claims. We included 51,734 patients who were diagnosed with primary insomnia from 2002 to 2004 as the test group and 258,715 nonprimary insomnia pa...

BACKGROUND Our Center recently conducted a systematic review of the manifestations and management of chronic insomnia in adults. The efficacy and safety of benzodiazepines and nonbenzodiazepines, relative to placebo, were compared indirectly. OBJECTIVES Determine how the results of indirect comparisons made in the review compare with the results of direct comparisons, as well as with estimate...

1111 Insomnia Subtypes and Excessive Daytime Sleepiness—Hara et al night) is often associated with anxiety disorders,11 while middle insomnia (difficulty in maintaining sleep) and terminal insomnia (early morning awakening) are often associated with disorders causing pain, adverse general health, and depression.12,13 To date, the only study to investigate the association between insomnia subtyp...

OBJECTIVE To evaluate the efficacy of benzodiazepines and zolpidem tartrate in chronic insomnia based on a quantitative review of literature. DATA SOURCES Articles from 1966 to 1996 were identified using MEDLINE, by a manual review of relevant journals, and from bibliographies of identified articles. STUDY SELECTION Studies using randomized, double-blind, placebo-controlled, parallel or cro...