An amino acid, 3S-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid, was isolated for the first time from the leaves of Cichorium endivia. The complete assignment of its (1)H and (13)C NMR spectroscopic data was carried out also for the first time based on extensive 1D and 2D NMR experiments. Cytotoxicity of this isolated compound against HCT-8 and HepG2 human cancer cell lines was evaluated for...

The effects of different concentrations of the hydroalcoholic extract of dried powdered leaves of Cichorium intybus L., on CCl4-induced hepatotoxicity in vivo in rats and CCl4-induced cytotoxicity in isolated rat hepatocytes were investigated. Rats received different concentrations of the extract by i.p. injection for 3 consecutive days before the injection of (3ml/kg) CCl4 (i.p.). Twenty four ...

The gene for a recently identified cDNA, 1-FEH IIa, encoding a fructan 1-exohydrolase was isolated and cloned from Cichorium intybus and a 1149 bp promoter fragment was characterized. An analysis of the genomic 1-FEH IIa sequence indicated that the gene (FEHIIa) consists of six introns and seven exons, which is similar to plant invertase genes. Like invertase genes, FEHIIa also contains the 9 n...

Although the Compositae harbours only two major food crops, sunflower and lettuce, many other species in this family are utilized by humans and have experienced various levels of domestication. Here, we have used next-generation sequencing technology to develop 15 reference transcriptome assemblies for Compositae crops or their wild relatives. These data allow us to gain insight into the evolut...

In this study, we aim to demonstrate, separately, the hepatoprotective activity of the total ethanolic extract as well as the defatted ethanolic extract of Cichorium intybus L., using adult Wister albino rats (120-170 g) as the experimental animals. The total as well as the defatted alcoholic extracts of Cichorium intybus L., seeds possess significant hepatoprotective activity; which may be att...

background & aim: organophosphates are frequently used as insecticides in households, in agricultural areas and veterinary, thus posing a risk for accidental dermal exposure or through inhalation. acute organophosphate poisoning causes thousands of human mortalities each year in developing countries.   material & methods: this study carried out to study an antitoxic effect of endemic ir...

The plant Cichorium intybus L., also known as Chicory, is found in different parts of the world and has a rich phytochemical composition. Within its spectrum action, been studied about performance against pathogenic microorganisms biofilm. Therefore, objective present study to realize literature review on antimicrobial antibiofilm actions species intybus. For this, searches were carried out dat...

Modern and sustainable production of safe and healthy high quality vegetables for human consumption is nowadays the goal of many producers. Chicory (Cichorium intybus L.) has become an important crop used as food in many countries over the past decade. In this work fi eld and glasshouse trials were conducted to compare phenolic profi les of hydroponically forced leaves and leaves produced as co...