نتایج جستجو برای: circular tub

تعداد نتایج: 68338  

Journal: :Physiological genomics 2006
Yun Wang Kevin Seburn Lawrence Bechtel Bruce Y Lee Jin P Szatkiewicz Patsy M Nishina Jürgen K Naggert

Tub is a member of a small gene family, the tubby-like proteins (TULPs), with predominant expression in neurons. Mice carrying a mutation in Tub develop retinal and cochlear degeneration as well as late-onset obesity with insulin resistance. During behavioral and metabolic testing, we found that homozygous C57BL/6J-Tub(tub) mice have a lower respiratory quotient than C57BL/6J controls before th...

Journal: :The European respiratory journal 2011
H Daito T Kikuchi T Sakakibara K Gomi T Damayanti J Zaini N Tode M Kanehira S Koyama S Fujimura M Ebina K J Ishii S Akira T Takai A Watanabe T Nukiwa

Mycobacteria are among the most common causes of hypersensitivity pneumonitis (HP), but controversy persists with regard to the involvement of the infectious potency of the organism in mycobacterial HP (hot tub lung). This study aimed to establish a mouse model of hot tub lung to clarify its pathophysiology. Mice were exposed intranasally to formalin-killed Mycobacterium avium from a patient wi...

Journal: :Scientific American 1909

2016
Maryam Moazzam Jazi Effat Ghadirzadeh Khorzoghi Christopher Botanga Seyed Mahdi Seyedi

The tree species, Pistacia vera (P. vera) is an important commercial product that is salt-tolerant and long-lived, with a possible lifespan of over one thousand years. Gene expression analysis is an efficient method to explore the possible regulatory mechanisms underlying these characteristics. Therefore, having the most suitable set of reference genes is required for transcript level normaliza...

2016
Meng-Yao Li Xiong Song Feng Wang Ai-Sheng Xiong

Parsley, one of the most important vegetables in the Apiaceae family, is widely used in the food, medicinal, and cosmetic industries. Recent studies on parsley mainly focus on its chemical composition, and further research involving the analysis of the plant's gene functions and expressions is required. qPCR is a powerful method for detecting very low quantities of target transcript levels and ...

2016
Wang Xiaojun Liu Yan Xu Hong Zhang Xianghong Li Shifeng Xu Dingjie Gao Xuemin Zhang Lijuan Zhang Bonan Wei Zhongqiu Wang Ruimin Darrell Brann Yang Fang

Silicosis is the most serious occupational disease in China. The objective of this study was to screen various proteins related to mechanisms of the pathogenesis of silicosis underlying the anti-fibrotic effect of N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) using proteomic profile analysis. We also aimed to explore a potential mechanism of acetylated α-tubulin (α-Ac-Tub) regulation by Ac-SD...

2011
S. Huhulescu M. Simon M. Lubnow M. Kaase G. Wewalka A. T. Pietzka A. Stöger W. Ruppitsch F. Allerberger

Community-acquired pneumonia due to Pseudomonas aeruginosa in previously healthy individuals is a rare disease that is associated with high fatality. On 14 February 2010 a previously healthy 49-year-old woman presented to an emergency room with signs and symptoms of pneumonia, 2 days after returning from a spa holiday in a wellness hotel. Blood cultures and respiratory specimens grew P. aerugin...

Journal: :Protein engineering, design & selection : PEDS 2009
Hailing Yang Fernando Cabral Rajat Bhattacharya

Tub 2.1, a monoclonal antibody commonly used to measure cellular tubulin content, is widely believed to recognize all beta-tubulin isotypes. Though it has been used for more than two decades, the epitope for this antibody is not well established. We report for the first time that contrary to common belief, this antibody does not react with all isotypes of beta-tubulin. Of the seven vertebrate b...

Journal: :European Respiratory Review 2013

Journal: :Ruminants 2021

The objective of this study was to evaluate the growth performance responses and liver trace mineral status newly weaned steer calves offered a low-moisture, molasses-based block “stress tub” containing organic sources minerals Saccharomyces cerevisiae fermentation culture during first 21-d 42-d feedlot receiving phase. Newly weaned, single source Charolais x Angus (n = 46; body weight [BW] 240...

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