We compared the clinical usefulness of serum myoglobin and creatine kinase MB (CK MB) isoenzyme determinations in the early diagnosis of acute myocardial infarction in 109 consecutive patients admitted to a coronary care unit. Of these, 37 patients were diagnosed as having definite infarction, three possible infarction, and 69 no infarction, using World Heath Organisation criteria. Blood sample...

We have clinically evaluated the Dade "Cardiozyme" immunoinhibition procedure for determination of creatine kinase isoenzyme MB (CK-MG) in 71 patients who were suspected of having had an acute myocardial infarction. Electrophoresis for CK-MB was also carried out. On the basis of diagnostic sensitivity and specificity for myocardial infarction, we found the Dade procedure for CK-MB to be somewha...

Serial determinations of serum creatine kinase (CK), cardio-specific isoenzyme of CK (CK-MB), glutamic oxaloacetic transaminase (GOT) and alpha-hydroxybutylate dehydrogenase (HBD) were made in 29 consecutive patients undergoing aorta-coronary (AC) bypass grafting, and the results were compared with those in 31 patients with acute myocardial infarction (AMI). Postoperatively, all patients had an...

prolonged or repeated exposure to cement dust, depending on the duration, level of exposure and individual sensitivity has health implications on the skin, eyes, respiratory and haematological systems. this study assessed cardiovascular disease risk factors and cardiac markers among cement workers of nigerian origin to determine the effects of duration of exposure to cement dust on these parame...

In a multicenter study we compared three tests for ischemic myocardial injury (IMI): a new, automated enzyme immunoassay for S-troponin T (S-TNT; Boehringer Mannheim) and two S-creatine kinase (CK) isoenzyme MB assays (mass and catalytic concentrations). For critical evaluation of clinical sensitivity, we studied 243 cases with an IMI prevalence of 43% and an 18% prevalence of cases with unstab...

Objective: To investigate the diagnostic value of creatine kinase-myocardial band (CK-MB), myoglobin (Myo) and cardiac troponin T (cTnI) in acute myocardial infarction (AMI) and heart failure (HF). Methods: Fifty patients with AMI, 50 HF patients and 50 normal subjects in hospital from January 2015 to December 2016 were enrolled. The levels of CK-MB, Myo and cTnI were measured for the analysis ...

BACKGROUND There is uncertainty as to the comparative prognostic value between cardiac troponin I (cTnI) and CK-MB in acute coronary syndrome (ACS). OBJECTIVE To compare the prognostic value between cTnI and CK-MB mass in patients with ACS without ST-segment elevation. METHODS 1,027 patients were analyzed in a prospective way in a tertiary cardiology center. Combinations of biomarkers were ...

We describe the case of an elderly woman whose symptoms and electrocardiographic pattern initially suggested acute myocardial infarction. The value for total serum creatine kinase (EC 2.7.3.2; CK) was 737 U/L (reference interval: 22269 U/L), and electrophoresisfor CK isoenzymes demonstrated two bands, the more anodal migrating to the CK-MB region and the second migrating between the CK-MB and C...

In an effort to clarify the issue of potentially false increases in creatine kinase (EC 2.7.3.2) MB isoenzyme (CK-MB) in uremia, we evaluated the CK profile of 84 persons undergoing chronic maintenance hemodialysis. We compared the performance of a new commercial two-site chemiluminometric immunoassay of CK-MB (Magic Lite; Ciba Corning Diagnostics) with that of electrophoresis on agarose gel (C...