Background/Introduction Postoperative coronary artery spasm (CAS) is an infrequent life-threatening event after cardiac surgery. We have suggested to cross clamp aorta for short time and to inject nitrates into the aortic root in case of suspicion of CAS. It enable us to deliver nitrates especially into coronary arteries during operation (patent RU 2552890). Another method is conventional coron...

BACKGROUND Use of a minimally invasive approach for isolated aortic valve surgery is increasing. However, management of the root and/or ascending aorta through a mini-invasive incision is not so frequent. The aim of this study is to report our initial experience with surgery of the ascending aorta through a ministernotomy approach. METHODS We retrospectively analyzed 102 patients treated for ...

BACKGROUND Challenges with small-for-size grafts are a critical issue in the liver transplantation field, and a reliable and reproducible animal model is required. METHOD We performed 50 orthotopic liver transplantations in pigs with a 30% graft, and retrospectively investigated the learning curves. We modified our surgical procedures according to our experience. Here, we describe our current...

The properties of large conductance Ca(2+)-dependent K+ channels in smooth muscle cells (SMC) isolated from normal and atherosclerotic human aorta were studied using the patch-clamp technique. It was shown that SMC from normal human aorta possess a homogeneous population of normal Ca(2+)-dependent K+ channels. In atherosclerotic aorta two kinetically different types of these channels could be d...

OBJECTIVES The higher risk of adverse aortic events in patients with bicuspid aortic valve (BAV) disease and ascending aorta aneurysm is known, but the management of moderate aortic root dilatation in younger patients is a controversial issue. The aim of the study was to compare survival in patients with or without root replacement. METHODS We reviewed 166 consecutive patients with BAV diseas...

traumatic false aneurysm of the thoracic aorta is not uncommon. but accordingly this case is unusual in its ten year delay between injury and presentation and treatment. a victim of the iran-iraq war is presented with a false aneurysm of the thoracic aorta ten years after a bullet injury to the chest and thoracic spine. penetrating chest wounds, mechanisms of injury and diagnosis are also discu...

Reports have shown the antioxidant, hypotensive, hypolipidemic and vasodilatory effects of grape (Vitis vinifera L.) seed extract. We have recently shown the relaxatory effect of grape leaf extract on rat uterus and reduction of frog heart rate and contractility. The aim of the present study was to investigate the relaxant effect of Vitis vinifera leaf hydroalcoholic extract (VLHE) on rat thora...

mycotic pseudoaneurysm of the ascending aorta is rare in patients undergoing coronary artery bypass graft (cabg) and usually caused by staphylococcus aureus. we describe a patient with a mycotic pseudoaneurysm of the ascending aorta at the proximal vein graft anastomosis site after cabg. culture from the sinus tract of the sternum and from the aneurysm sac was klebsiella pneumoniae. surgical te...

Aortic dissection occurs when a tear develops in the wall of the aorta, which is rare in the young population. This fatal disorder is hard to diagnose, especially in young patients. We present the case of aortic dissection in a 15-year-old boy referred to the Emergency Department of Yazd University of Medical Sciences in November 2015. The patient presented to our department with sudden acute c...

OBJECTIVES We reviewed the initial patient series (n=116) of our institution performing minimally invasive coronary artery bypass grafting (CABG) (n=79), mitral valve surgery (n=1), or atrial septal closure (ASD) procedures (n=26) using an endoaortic occlusion system. With this technique relevant intra-aortic pressures are exerted on the aortic wall during the clamping time. This might lead to ...