We present a comprehensive new framework for handling biologically accurate models of molecular evolution. This model provides a systematic framework for studying models of molecular evolution that implement heterogeneous rates, conservation of reading frame, differing rates of insertion and deletion, customizable parametrization of the probabilities and types of substitutions, insertions, and ...

Objectives: The present study aimed to provide an estimation of the current financial burden of renal transplantation therapy for insurance organisations.Methods: An Excel-based model was developed to determine the treatment costs of current clinical practice in renal transplantation therapy (RTT). Inputs were derived from Ministry of Health and insurance organizations` database, hospital and p...

I will review several statistical estimation problems which arise in the computational anatomy setting, casting three problems of statistical estimation as examples of parameter estimation in the context of many templates: (i) disease estimation, (ii) segmentation and (iii) template estimation. Then I will discuss one of the central questions in neurodegenerative diseases today, the staging of ...

In the first part of this paper, an analysis of the data collected during the American Association of State Highway Officials (AASHO) Road Test, based on probabilistic duration modeling techniques, is presented. Duration techniques enable the stochastic nature of pavement failure time to be evaluated as well as censored data to be incorporated in the statistical estimation of the model paramete...

PURPOSE Estimation of body fluid volume in hyponatremia is useful for diagnosis and therapeutic decision-making. Physical examination has been generally used to estimate body fluid volume, but it depends on the physician's abilities. Bioimpedance spectroscopy has been suggested to be a reliable method for the estimation of body fluid volume. Therefore, this study investigated whether bioimpedan...

background: due to unpredictability of events in psychiatry environment and replacement of routine clinical experiences with some assignments such as therapeutic communication with patients, clinical training in such environments has been associated with many problems which require continuous review and evaluation.  the purpose of the present research was to determine the effect of applying por...

abstract:             partial knowledge is one of the main factors to take into account when dealing with the improvement of administration of multiple choice questions (mcq). various strategies have been proposed for this factor in traditional testing environment. so this study proposed a confidence based assessment (cba) as a sufficient solution & want to compare the effect of cba scoring sys...