mara activates two membrane dependent mechanisms of resistance to different antibiotics, such as ciprofloxacin and tetracycline, including promotion of outflux and inhibition of influx of antibiotics. thus, mara causes multiple antibiotic resistance phenotype. the activation of these mechanisms needs overexpression of mara. this could happen through mutation in marr. thus, the aim of this study...

background:  cytotoxic t lymphocyte–associated antigen 4 (ctla-4) molecules are expressed on t-cells and inhibit their function by inhibiting activation of subsequent t-cell molecular pathways. blocking of ctla-4 inhibits the growth of malignant tumor cells. anti-ctla-4 monoclonal antibodies activate the immune system against cancer. due to several advantages of single-chain antibodies (scfvs) ...

poplar trees are becoming extremely important as fast growing species due to the increasing need for wood and decreasing productivity of some lands in iran. the present study aimed to find the effect of canopy of poplar clones as one of the most important effective factors on soil properties compared to the distances inter-row trees. five poplar clones and species included: populus euramericana...

conclusions gp55 of human cmv is considered as an important candidate for immunotherapy. in this study, we selected three specific clones against gp55. the scfvs reacted only with the corresponding peptide in a positive elisa. the scfv2 with 68.8% neutralizing effect showed the potential to be considered for prophylaxis and treatment of cmv infections, especially in solid organ transplant recip...

background:the premature termination of high producer clones, which will be killed due to cell proliferation and proteins production antagonism, is one of the basic drawback in recombinant proteins technology. furtheremore, it is supposed some toxic proteins like interferon which we intended to clone and express, inhibit host cells’ proliferation. so, it is necessary to tightly control ifn-γ pr...

The anatomical structure and physical properties of wood change signifcantly among trees the same species even different parts tree. However, studies that characterize radial variation characteristics density clones are scarce, specifcally for rubber tree [Hevea brasiliensis (Will. ex Adr. De Juss.) Muell]. Thus, objective research was evaluating in Hevea clones. For this study, 30 trees, three...