objective: to study the effects of different matrices and co-culture systems on cultured limbal stem cells (lscs). materials and methods: limbal explants were co-cultured with limbal fibroblasts (lf) and/or mouse embryonic fibroblasts (mef) on filter inserts coated with amniotic membrane (am), matrigel (mat) and collagen type i (col). results: this study revealed that am facilitated the cell mi...

Understanding context-specific behavior of biological systems plays a fundamental role toward analyzing molecular mechanisms contributing to genetic diseases and the development of efficient therapeutic strategies [1]. The majority of genes show significant differences in expression levels in different tissues that reflect variations in biological pathways characteristic for a particular tissue...

background: the potential of plants as a safe and eukaryotic systems, are considered for producing recombinant therapeutic human protein today; but the expression level of heterologous proteins is limited by the post-transcriptional gene silencing (ptgs) response in this new technology. the use of viral suppressors of gene silencing can prevent ptgs and improve transient expression level of for...

Co-channel interference is a major factor in limiting the capacity and link quality in cellular communications. As the co-channel interference is modeled by lognormal distribution, sum of the co-channel interferences of neighboring cells is represented by the sum of lognormal Random Variables (RVs) which has no closed-form expression. Assuming independent, identically distributed (iid) RVs, the...

this paper contends that there has been a definitive and negative change in the trajectory of so-called islamic feminism. this change has been effected in large part in the west , as part of the growing discourse of euro-islam, european islam, indigenization of islam, etc., a discourse that comes not from governments (though it is mirrored, applauded and rewarded by governments in the region) b...

Gene co-expression network differential analysis is designed to help biologists understand gene expression patterns under different conditions. We have implemented an R package called MODA (Module Differential Analysis) for gene co-expression network differential analysis. Based on transcriptomic data, MODA can be used to estimate and construct condition-specific gene co-expression networks, an...

background: cell-based treatment approach using differentiated mesenchymal stem cells (mscs) and mature chondrocytes has been considered as an advanced treatment for cartilage repair. we investigated the differentiated level of these two cell types that is crucial for their repair capacity for cartilage defect at a co-culture micro mass system.   methods: passaged-2 mscs isolated from the mouse...

objective(s): the present day challenge is how to obtain germ cells from stem cells to treat patients with cancer and infertility. much more efforts have been made to develop a procedure for attaining germ cells in vitro. recently, human umbilical cord-derived mesenchymal stem cells (humscs) have been introduced with higher efficacy for differentiation. in this work, we tried to explore the eff...