Sickle cell trait is a relatively common condition in the African-American population. Individuals with this condition may have any of several complications under rare circumstances. We report a patient who presented with extensive compartment syndrome leading to death. A 31-year-old African-American male with known history of sickle cell trait developed extensive compartment syndrome followed ...

the development of complications after procedure, such as age, heart and lung condition, electrolyte imbalance, advanced liver disease, and liver coagulopathy. Obstructive jaundice, especially in patients with high bilirubin level can be more challenging due to the risks of infection and bleeding [3, 4]. Hyperbilirubinemia can lead to hemostasis impairment due to poor absorption of vitamin K. B...

Minor postoperative bleeding is the most common complication of cutaneous surgery. Because of the commonality of this complication, hemostasis is an important concept to address when considering dermatologic procedures. Patients that have a bleeding diathesis, an inherited/acquired coagulopathy, or who are on anticoagulant/antiplatelet medications pose a greater risk for bleeding complications ...

Rev Esp Cardiol. 2010;63(3):362-76 369 hypertension, and high pulmonary-capillary wedge pressure, may facilitate the risk of development of alveolar haemorrhage in patients treated with GP IIb/IIIa inhibitors, whereas others, believe that pulmonary disease does not necessarily define a subgroup of patients particularly at risk for this complication. The unpredictable and potentially lethal cour...

Acute promyelocytic leukemia (APL) represents 15 % of acute myeloid leukaemia. Prior to tretinoin usage, the treatment of APL was difficult and remission rates were low especially in developing countries due to mortality resulting primarily from bleeding'. APL is associated with a coagulopathy which may be due to a combination of disseminated intravascular coagulation and primary fibrinolysis. ...

Coronavirus disease (COVID-19) can induce coagulopathy at the base of sepsis-induced coagulopathy (SIC), which is an important cause of death in these patients. Cytokine storm causes imbalance in coagulation and fibrinolytic system. A combination of hypercoagulability state, decrease or inhibition of fibrinolysis and endotheliopathy causes thromboembolic events. Underlying diseases such as diab...

Hemangioma is the most common congenital benign liver tumor. It affects mostly female, with incidence of 0.4- 20%. Giant hemangioma induce Kasabach Merritt syndome, a life threathening coagulation disorder which occur due to consumptive coagulopathy: trombocyte sequestration and agregation inside hemangioma. The mortality rate around 60%, cause multiorgan complication may end up sepsis. core ma...

Ventricular wall rupture after mitral valve replacement is an uncommon complication but often lethal. We report the autopsy findings in a case of a 77 year old woman suffering double mitral disease who underwent unsuccessful replacement of the mitral valve using a Saint Jude (ONXM 27/29) mechanical prosthesis. The patient developed consumptive coagulopathy and a type I left ventricular rupture....

Costello syndrome is characterised by dwarfism, unique cutaneous lesions, a distinct facial gestalt, and mental retardation. There have been no detailed reports of severe spinal deformities requiring surgical treatment as a complication of Costello syndrome. We report a case of a 10-year-old girl with progressive scoliosis associated with Costello syndrome. She underwent anterior release and po...

Purpose Macrophage Activation Syndrome (MAS, alternatively known as secondary Hemophagocytic Lymphohistiocytosis (HLH)) is a potentially life-threatening complication of many rheumatologic, infectious, and malignant diseases. It is characterized by the acute onset of disseminated intravascular coagulopathy and multi-system organ dysfunction in the setting of overwhelming inflammation. As a resu...