Photoreceptor differentiation in the Drosophila eye disc progresses from posterior to anterior in a wave driven by the Hedgehog and Decapentaplegic signals. Cells mutant for the hyperplastic discs gene misexpress both of these signaling molecules in anterior regions of the disc, leading to premature photoreceptor differentiation and overgrowth of surrounding tissue. The two genes are independen...

In view of the developmental approach to sexual behavior, this article presents the stages of sexual behavior leading to coitus in four grades of high school students in Israel and the sociodemographic factors associated with initiating coitus. Analyses were based on data from the first national study dealing comprehensively with sexuality in 30 years. A self-administered questionnaire was comp...

Vaginal rupture leading to pneumoperitoneum is well documented to occur after hysterectomy or surgery. However, it is extremely rare in a young woman following conventional intercourse. We report one such case. A 16-year-old woman presented to the accident and emergency department with a clinical picture of an acute abdomen. Results of radiography showed gas under the diaphragm, suggesting the ...

The goal of this study was to examine the effects of early and adverse experiences with sex and alcohol on adolescent drinking the year before and during pregnancy. Pregnant adolescents, recruited at an outpatient prenatal clinic, were interviewed about their substance use. A subsample was asked about their first sexual experiences. Associations among early experiences with alcohol and sex and ...

Sexual behaviour of 75 normal married females was studied. Most of them had a healthy attitude to sex. Frequency of sexual activity decreases with age and duration of marriage. Median frequency for 21-30years age was 2/week, for 31- 40years was 1.4/week and for 41-50 years was 0.5/week. Frequency of coitus did not correlate with socio-economic status. Nearly 52% women had more than 50% satisfac...