Fourteen patients with a variety of ataxic disorders were given choline chloride, double blind for six weeks, in an attempt to improve gait and manual dexterity. One patient withdrew before receiving the active drug, twelve patients showed no functional improvement, but one achieved greater mobility; his response, which was dose dependent, ceased when choline was stopped and was reproducible.

Propolis is a widely used medicine that may be found in both its pure form and when combined with othernatural ingredients over-the-counter preparations, cosmetics, health foods. Some customers develop alcohol sensitivity after using ethanol, which common solvent to extract propolis. As propolis solvents, various Natural Deep Eutectic Solvents (NaDES) were examined this study. Choline chloride,...

Abstract The existing CO 2 absorption by deep eutectic solvents is limited the unavoidable water problem during use. In this study, we prepared three with different alcohol aminations and added contents to discuss effect of content on carbon dioxide solvents. All have a low melting point at room temperature as liquid high thermal stability, where choline chloride-diethanolamine viscosity. Anhyd...

The choline concentration used in the growth medium influences the density of mitochondria produced by the chol-1 mutant of Neurospora. Isopycnic centrifugation in sucrose gradients can be used to determine the density of mitochondria, and can resolve into two populations, mitochondria derived from a mixture of cells grown at low (1 microg/ml choline chloride) and high (10 microg/ml choline chl...

The enzymatic preparation of biodiesel has been hampered by the lack of suitable solvents with desirable properties such as high lipase compatibility, low cost, low viscosity, high biodegradability, and ease of product separation. Recent interest in using ionic liquids (ILs) as advanced reaction media has led to fast reaction rates and high yields in the enzymatic synthesis of biodiesel. Howeve...

Perinatal choline supplementation in rats is neuroprotective against insults such as fetal alcohol exposure, seizures, and advanced age. In the present study we explored whether dietary choline supplementation may also confer protection from psychological challenges, like stress, and act as a natural buffer against stress-linked psychological disorders, like depression. We previously found that...

Deep eutectic solvent treatment to overcome lignocellulose resistance deconstruction has great potential for the production of biofuels and bioproducts. Most investigations have been focused on optimizing sugar yield from specific feedstocks. However, little is known about interaction between deep cellulose during pretreatment, post-treatment accessibility enzymes, lignin fractionation. We eval...