Background Late gadolinium enhancement (LGE) with CMR is commonly assumed to represent myocardial fibrosis; however, comparative human histological data are limited, and there is no consensus on the most accurate method for LGE quantitation. We evaluated the relationship between CMR assessment of regional fibrosis and infarct size assessment using serial biomarkers after ST segment elevation my...

One of the fundamental advantages behind Adaptive Comparative Judging (ACJ) is that it is easier and more accurate to comparison judge a series of products, and to develop a rank order of achievement, than it is to score products using a more subjective method or rubric approach. Research in the field of comparative judging has shown very high levels of reliability and close correlations betwee...

In this article, we present a comparative study of a developed new formal mathematical model of risk assessment (FoMRA) with expert methods of risk assessment in the information systems (IS). Proposed analysis verified the correctness of theoretical assumptions of developed model. In the paper, the examples of computations illustrating the application of FoMRA and known and accepted throughout ...

Standardization of photography in plastic surgery is fundamental for pre-operative surgical planning, comparative post-operative assessment, and demonstration of surgical results.1 In rhinoplasty, slight changes in patient or camera position can lessen nasal hump, vary nose size, and alter skin tension.2 In order to prevent these common errors, photographic standardization with high-quality equ...

There exist numerous algorithms that cluster data-points from largescale genomic experiments such as sequencing, gene-expression and proteomics. Such algorithms may employ distinct principles, and lead to different performance and results. The appropriate choice of a clustering method is a significant and often overlooked aspect in extracting information from large-scale datasets. Evidently, su...

The matrisome is a complex and heterogeneous collection of extracellular matrix (ECM) and ECM-associated proteins that play important roles in tissue development and homeostasis. While several strategies for matrisome enrichment have been developed, it is currently unknown how the performance of these different methodologies compares in the proteomic identification of matrisome components acros...

OBJECTIVE To compare the cost-effectiveness of interventions to reduce pneumonia mortality through risk reduction, immunization and case management. METHODS Country-specific pneumonia burden estimates and intervention costs from WHO were used to review estimates of pneumonia risk in children under 5 years of age and the efficacy of interventions (case management, pneumonia-related vaccines, i...