OBJECTIVE Prefrontal mechanisms are implicated in obsessive-compulsive disorder. The authors investigated whether prefrontal repetitive transcranial magnetic stimulation influenced obsessive-compulsive disorder symptoms. METHOD Twelve patients with obsessive-compulsive disorder were given repetitive transcranial magnetic stimulation (80% motor threshold, 20 Hz/2 seconds per minute for 20 minu...

Comorbidity is known to occur among various psychiatric disorders. About the third of the patients with Obsessive Compulsive Disorder have major depressive disorder and anxiety disorder but coexistence of Obsessive Compulsive Disorder with mania is rare to see. Here we report a case of Obsessive Compulsive Disorder where manic phase was accompanied by obsessions of contamination and pathologica...

obsessive-compulsive disorder (ocd) is a psychiatric disorder manifested by thoughts and impulses that produce anxiety and result in patients performing repetitive rituals. treatment generally consists of cognitive behavioral intervention and serotonin reuptake inhibitors. up to 40% of patients will have functional impairment that significantly affects their quality of life. in the late 1990’s,...

objective: although treatments with demonstrated efficacy exist for obsessive-compulsive disorder (ocd) researches on the effectiveness of combined treatment versus psychotherapy or drug treatment are controversial. the aim of this study was to compare the efficacy of metacognitive therapy (mct), fluvoxamine and the combination of mct with fluvoxamine treatment in treating patients with ocd. me...

background: obsessive-compulsive disorder (ocd) symptoms and the related disorders are subsumed under chronic psychiatric disorders which are of psychosocial and therapeutic importance. in most studies, the mean age of onset of significant ocd symptoms is adolescence period. the aim of this study was to evaluate ocd symptoms, tic disorder, body dysmorphic disorder (bdd) and trichotilomania amon...

OBJECTIVE A substantial body of evidence suggests that obsessive-compulsive disorder has a genetic component, and substantial candidate genes for the disorder have been investigated through association analyses. A particular emphasis has been placed on genes related to the serotonergic system, which is likely to play an important role in the pathogenesis of obsessive-compulsive disorder. The ge...