نتایج جستجو برای: concentration response curve
تعداد نتایج: 1418229 فیلتر نتایج به سال:
Background and aims: Exposure to the normal hexane can induce dysfunction of the nervous system and color vision impairment. Occupational risk assessment is established according to no observed adverse effect levels (NOAEL). Recently, because of the NOAEL’s limitations, the benchmark responses were applied for risk assessment. The study’s aim is an analysis of benchmark response in occupational...
The following description of the package grofit was also published as Kahm et al. (2010). The grofit package was developed to fit many growth curves obtained under different conditions in order to derive a conclusive dose-response curve, for instance for a compound that potentially affects growth. grofit fits data to different parametric models and in addition provides a model free spline metho...
formaldehyde in small quantities is commonly analyzed by spectrophotometric methods. one of the most-commonly used spectrophotometric techniques for this purpose is based on the reaction with chromotropic acid. because of its simplicity, sensitivity, selectivity and its low cost, it is still widely used. investigations for replacing the concentrated sulfuric acid with other acids or using more ...
In 18 clinically stable asthmatic patients histamine inhalation challenges were performed with a Wright's nebuliser and tidal volume breathing for two minutes on two to four occasions for each subject at a maximum interval of two weeks. The response was measured in terms of specific lung conductance (sGL) by the subtraction technique, maximum partial and maximum complete expiratory flow at 40% ...
Generally, doses greater than 2Gy can produce acute biological effects in humans. For this reason, to measure and record the cumulative dose, especially in radiation users, the need for a personal dosimeter has been strongly felt by the researchers. The purpose of this study is to introduce retrospective dosimetric techniques, in particular the use of nails as a natural tool for determining cum...
background: the purpose of this study was to characterize the pharmacokinetic parameters of mycophenolic acid (mpa) in iranian kidney transplant patients. methods: plasma mpa concentration of mycophenolate mofetile (mmf) 1 gram two times a day was measured in 21 iranian kidney transplant recipients receiving treatment. patients who entered the study had been transplanted for more than 3 months ...
the hydrograph at watershed outlet can be expressed as hydrological response of watershed to geomorphological behavior. in present study with the aid of the gis and the concept of instantaneous unit hydrograph, the watershed response was simulated. in present physical method, the iuh is derived from three parameters of time of concentration, storage coefficient and time-area curve of the basin....
TDM and exposure–response relationships TDM is the measurement and interpretation of drug concentrations in biological fluids so as to determine the correct drug dosage for an individual patient.1 The technique requires that dose be correlated with exposure and that exposure be correlated with pharmacodynamic (PD) response. Exposure metrics include the pharmacokinetic (PK) parameters: area unde...
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