The effects of early-onset blindness on the development of the visual system have been explained traditionally by the stabilization of transient connections through Hebbian competition. Although many of the findings from congenital cataract and congenital blindness are consistent with that view, there is inconsistent evidence from studies of visual cognition in children treated for visual depri...

purpose: to compare the outcomes and complications of mitomycin-c (mmc) trabeculectomy and ahmed glaucoma implant (agi) for treatment of aphakic glaucoma following congenital cataract surgery in children £ 16 years of age. methods: in a randomized clinical trial, eligible children were randomly assigned to mmc trabeculectomy or agi. aphakia was due to previous anterior lensectomy and vitrectomy...

Cataract, opacification of the crystalline lens of the eye, is the most common cause of blindness in the world [1]. The World Health Organization estimates that 45 million people in the world are blind, 19 million of them as a result of cataract [1]. Cataracts may be broadly divided into adult onset and childhood onset (either congenital or infantile). Congenital cataract is defined as cataract...

BACKGROUND/AIMS Congenital ocular anomalies contribute significantly to childhood visual morbidity, with congenital cataract being a major cause of visual impairment throughout the world. As in many other countries, a National Congenital Anomaly System (NCAS) exists in England and Wales to monitor the frequency of ocular and other anomalies in order to identify new public health hazards and inf...

PURPOSE To describe the incidence of unilateral congenital cataract associated with minimal (ultrasonically undetectable) levels of persistent fetal vasculature in the first 18 months of the life and to report surgical methods for intraocular lens implantation, using 25-gauge vitrectomy system. METHODS Retrospective review was made on 16 consecutive patients with bilateral or unilateral conge...

OBJECTIVE To determine the relative contributions of mutations in congenital cataract cases in an Indian population by systematic screening of genes associated with cataract. METHODS We enrolled 100 congenital cataract cases presenting at the Dr. R. P. Centre for Ophthalmic Sciences, a tertiary research and referral hospital (AIIMS, New Delhi, India). Crystallin, alpha A (CRYAA), CRYAB, CRYGs...

Introduction Amblyopia is the leading cause of reduced vision in children following cataract surgery. It may develop as a consequence of visual deprivation, anisometropia, or strabismus. Methods: Animal studies as well as clinical series were reviewed focusing on the pathophysiology and treatment of aphakic and pseudophakic amblyopia. Results: Excellent visual outcomes have been reported in chi...

Congenital Cataract.?The following three cases are, I think, worth recording: first, because congenital cataract, though by no means rare, is much less common than other forms; and secondly, because the variety about to be described seems to occur in England only in one eye. See Mr. Crichetts's paper in the Royal London Ophthalmic Hospital Reports of July 1861, page 188. If I be right in its id...