Although glaucoma is a major global cause of blindness, the lack of a uniform definition of the disease in its different forms makes it difficult to assess its public health impact. By considering the common features of glaucoma, we have analysed available data on the three main forms of the disease: congenital/hereditary glaucoma, primary open-angle, and primary angle-closure glaucoma. A simpl...

PURPOSE Primary congenital glaucoma (PCG), a severe form of glaucoma that presents early in life, is an autosomal recessive eye disorder that results from defects in anterior eye segment. Null mutations in LTBP2 were reported in patients with PCG in Pakistani and Iranian families. This study was aimed to identify the mutation profile of the LTBP2 gene in north Indian patients with PCG. METHOD...

PURPOSE Congenital microcoria is a rare autosomal dominant developmental disorder of the iris associated with myopia and juvenile open angle glaucoma. Linkage to the chromosomal locus 13q31-q32 has previously been reported in a large French family. In the current study, a three generation Asian Indian family with 15 congenital microcoria (pupils with a diameter <2 mm) affected members was studi...

Purpose: The goal of this retrospective study was to evaluate how long, on average, after a 360 trabeculotomy procedure secondary surgery needed for patients with congenital and glaucoma.&#x0D; Methods: IRB approval received from the Indiana University School Medicine access digital patient charts Riley Children’s Hospital’s department ophthalmology. Kruska-Wallis test utilized average number d...