treated × 6 months) were included. Whole blood VL was determined by real-time PCR at a central laboratory before therapy (baseline, BL) and periodically for 6 months. Results. In subjects treated for 6 months, increases in BL VL correlated with decreased probability of better hearing outcomes at 12 months (Figure 1), but clinically meaningful VL thresholds that predict SNHL were not identified ...

OBJECTIVES To determine the prevalence of refractive and nonrefractive ophthalmologic abnormalities in children with sensorineural hearing loss (SNHL) and to evaluate the overall utility of routine ophthalmological examination in children with SNHL. DESIGN An institutional review board-approved retrospective analysis of ophthalmologic findings in children (18 years and younger) with SNHL seen...

OBJECTIVES The aim of this study was to investigate changes in the hearing thresholds during the first year of life in infants who failed the newborn hearing screening (NHS) test and of infants treated in the neonatal intensive care unit (NICU). METHODS From March 2007 to November 2010, 193 healthy infants who failed the NHS test and 51 infants who were treated in the NICU were referred for e...

Introduction  Several authors have demonstrated the relationship between sudden sensorineural hearing loss (SNHL) and systemic autoimmune diseases (SAD). Immune-mediated SNHL can rarely present as unilateral sudden SNHL and manifests itself in the contralateral ear only after years. It presents clinical relevance for being one of the few SNHL that may be reversible given that early and appropri...

Background: Humans convey their emotions and information to one another through language. Delayed or poor speech can have a profound effect on the social professional life of person.
 Aim Objectives: A study children with poor/delayed in tertiary care centre western U.P. Objectives were as follows • To risk factors for congenital hearing loss poor/no speech. screen them regarding status. a...

PURPOSE The incidence of sensorineural hearing loss (SNHL) after treatment with combination of intensity-modulated radiation therapy (IMRT) and cisplatin-based chemotherapy in nasopharyngeal carcinoma (NPC) patients was evaluated, and relationships of SNHL with host factors, treatment-related factors, and radiation dosimetric parameters were investigated. METHODS Fifty-one NPC patients treate...

Department of Radiology, Otolaryngology-Head and Neck Surgery, Yonsei University Wonju College of Medicine, Wonju, Korea. Received September 3, 2003 ; Accepted February 13, 2004 Address reprint requests to : Ki-jun Sung, M.D., Department of Radiology, Wonju College of Medicine, Yonsei University, Wonju Christian Hospital, 162 Ilsan-dong, Wonju, Kangwon-do, 220-701, Korea, Tel. 82-33-741-1475 Fa...

INTRODUCTION Serum Anti endothelial Cell Antibodies (AECAs) play a prominent role in idiopathic Sensorineural Hearing Loss (SNHL) in that they induce vascular damage (immune mediated). The of the current study is To compare AECAs in serum and perilymphatic fluid of idiopathic SNHL children (<15y) undergoing cochlear implant surgery. METHODS This was a cross sectional study performed in the co...

During the past three to four decades, the incidence of acquired sensorineural hearing loss (SNHL) in children living in more developed countries has fallen, as a result of improved neonatal care and the widespread implementation of immunisation programmes. The overall decrease has been accompanied by a relative increase in the proportion of inherited forms of SNHL. The contribution made by one...

Sensorineural hearing loss (SNHL) is a common disability in the world; however, at present, options for the pharmacological treatment of SNHL are very limited. Previous studies involving human temporal bone analyses have revealed that the degeneration of the cochlea is a common mechanism of SNHL. A major problem for the development of novel pharmacotherapy for SNHL has been the limited regenera...