Case Report A female infant, aged 7 weeks, was admitted to Our Lady's Hospital for Sick Children, Dublin, on December 30. 1961. Her birth history had been normal and she had received B.C.G. vaccination a few days after birth. She had appeared well until about four days before admission to hospital, when she developed grunting laboured respirations and was reluctant to take feeds. On admission s...

Congenital tuberculosis is an unusual and severe clinical pattern of tuberculosis presentation of Mycobacterium tuberculosis infection. Furthermore, it usually has a difficult treatment. We report a two-month-old male infant who presented with fever, dyspnea and a diffuse micronodular pattern at x-ray; mother with severe tuberculosis. Treatment with the triple drug regimen was initiated, but th...

Congenital tuberculosis (TB) is a rare disease that is associated with high mortality. Mycobacterium tuberculosis, the causative agent, may be transmitted from the infected mother to the fetus by the transplacental route or by aspiration of infected amniotic fluid. Clinical symptoms and signs are not specific. Miliary patterns are the most common findings in the chest X-rays of many infants wit...

The prevalence of Mycobacterium tuberculosis infection in Taiwan has increased in recent decades. Extrapulmonary infection accounts for 40% of all tuberculosis cases. Here we report a seven-year-old girl with culture-proven tuberculous myositis manifested as progressive enlargement of chest wall mass. No congenital or acquired immune deficiency could be traced at presentation. After surgical ex...

This report describes the case of a pregnant woman with extrapulmonary tuberculosis which was not diagnosed during routine antenatal care despite a fourmonth history of intermittent fever, cough and weight loss. In the third trimester her condition deteriorated with progressive hepatic impairment, splenomegaly and ascites. Tuberculosis was diagnosed in the referral hospital. She was delivered b...

Abstract Introduction: although pediatric patients have comparatively fewer cases of COVID-19, children with Down Syndrome exhibit comorbidities such as immunodeficiency, diabetes and, in this perspective, are considered a population at risk for severe COVID-19. In addition, the literature also points to an unfavorable perspective on co-infection Mycobacterium tuberculosis, important comorbidit...

Author Disclosure Drs Satti, Ali, and Weitkamp have disclosed no financial relationships relevant to this article. This commentary does not contain a discussion of an unapproved/ investigative use of a commercial product/ device. Abstract The purpose of this two-part series on congenital infections is to provide the reader with an update on recent controversies and advances for a selected group...