PURPOSE/METHODS To report a rare case of a tumor in a conjunctival location, a giant cell collagenoma. Tissue was stained with hematoxylin-eosin, periodic acid-Schiff, and Masson's trichromic stain and studied by immunohistochemistry. RESULTS/CONCLUSION The clinical and histopathologic features of conjunctival giant cell collagenoma are similar to characteristics of the same tumor occurring i...

PURPOSE Local proliferation of macrophages has been reported to augment the inflammatory response in various human and experimental diseases. Macrophage accumulation in the submucosa is also an important feature in the pathogenesis of ocular cicatricial pemphigoid (OCP). In the present study, the role of local proliferation of macrophages in conjunctiva affected by OCP and the relationship betw...

purpose : to assess the results of brachytherapy in patients with recurrent or incomplete excised conjunctival squamous cell carcinoma (scc) and malignant melanoma. methods : three patients underwent brachytherapy of one eye and one patient underwent brachytherapy of both eyes with ruthenium-106 (ru-106) plaques, all of them had a history of incomplete resection or recurrence of the tumor after...

PURPOSE Currently available anti-scarring regimens for glaucoma filtration surgery have potentially blinding complications and thus the need for alternative and safer agents. The effects of a new antibody to transforming growth factor (TGF)-beta2 on in vitro and in vivo conjunctival scarring and after glaucoma filtration surgery were investigated. METHODS The activity of a novel recombinant m...

PURPOSE To determine the clinical significance of postoperative conjunctival inflammation noted at the third or fourth week after intraoperative application of mitomycin C and amniotic membrane transplantation for pterygium. METHODS This retrospective study included 27 eyes of 23 patients with primary (n = 12) or recurrent (n = 15) pterygia. All cases were operated by extensive removal of sub...

PURPOSE The study was conducted to analyze, by in vivo confocal microscopy (IVCM), the conjunctival epithelial characteristics in untreated ocular hypertension (OH) and in topically treated primary open-angle glaucoma (POAG). METHODS The study included 30 eyes affected with untreated OH, 96 eyes with POAG receiving medical therapy, and 15 healthy control eyes. The main outcome measures were t...

PURPOSE To examine the expression pattern of insulin-like growth factor-binding protein (IGFBP)-2 in cultured primary pterygium fibroblasts and compare it with expression in normal conjunctival fibroblasts. METHODS Profile of gene expression by normal conjunctival and primary pterygium fibroblasts was performed by using a cDNA microarray. The overexpression of IGFBP-2 thus identified was furt...