Enzymes are one of the most important biomolecules which has a wide range of applications in industrial as well as biomedical field. They are important due to their many useful properties. Their development, to a great extent, has been possible due to the availability of microbial sources. Microorganisms are of much attention because they can be produced economically and are amenable to genetic...

The history and origins of proficiency testing of clinical laboratories are reviewed. Since the introduction of proficiency testing in the late 1940s, dramatic improvement in laboratory performance has been demonstrated. Nonetheless, the poor performance found two decades earlier was summoned to support the passage of the Clinical Laboratory Improvement Act of 1967 (CLIA '67).