A novel therapy is demonstrated utilizing magnetic nanoparticles for the dual purpose of delivering microRNA and inducing magnetic hyperthermia. In particular, the combination of lethal-7a microRNA (let-7a), which targets a number of the survival pathways that typically limit the effectiveness of hyperthermia, with magnetic hyperthermia greatly enhances apoptosis in brain cancer cells.

this study investigated the applicability of polyethylene glycol (peg-4000) coated fe3o4 magnetic nanoparticles for the selective removal of toxic pb (ii) ion from wastewater. the fe3o4 magnetic nanoparticles of 24 nm were synthesized using a coprecipitation method and characterized by scanning electron microscopy (sem), vibratingsample magnetometer (vsm), and x-ray diffraction (xrd). sem image...

Background: Nowadays, magnetic nanoparticles (MNPs) have received much attention because of their enormous potentials in many fields such as magnetic fluid hyperthermia (MFH). The goal of hyperthermia is to increase the temperature of malignant cells to destroy them without any lethal effect on normal tissues. To investigate the effectiveness of cancer therapy by magnetic fluid hyperthermia, Fe...

This study investigated the applicability of polyethylene glycol (PEG-4000) coated Fe3O4 magnetic nanoparticles for the selective removal of toxic pb (II) ion from wastewater. The Fe3O4 magnetic nanoparticles of 24 nm were synthesized using a coprecipitation method and characterized by Scanning electron microscopy (SEM), vibratingsample magnetometer (VSM), and X-ray diffraction (XRD). SEM image...

Multifunctional core-shell nanocomposites with a magnetic core and a silica shell doped with lanthanide chelate have been prepared by a simple method. First, citric acid-modified magnetite nanoparticles were synthesized by a chemical coprecipitation method. Then the magnetite nanoparticles were coated with silica shells doped with terbium (Tb(3+)) complex by a modified Stöber method based on hy...

Nanostructured magnetic systems have many applications, including potential use in cancer therapy deriving from their ability to heat in alternating magnetic fields. In this work we explore the influence of particle chain formation on the normalized heating properties, or specific loss power (SLP) of both low- (spherical) and high- (parallelepiped) anisotropy ferrite-based magnetic fluids. Anal...

Iron oxide nanoparticles (IOs) are intrinsically theranostic agents that could be used for magnetic resonance imaging (MRI) and local hyperthermia or tissue thermal ablation. Yet, effective hyperthermia and high MR contrast have not been demonstrated within the same nanoparticle configuration. Here, magnetic nanoconstructs are obtained by confining multiple, ∼ 20 nm nanocubes (NCs) within a deo...

Mn-doped nanocrystalline ZnO particles have been successfully synthesized at low temperature (80 ̊C) by the coprecipitation method using zinc sulfatehepta hydrate and NaOH. The structural and magnetic properties have been characterized using X-ray diffraction (XRD), Energy dispersive x-ray, vibrating sample magnetometer and electron spin resonance. XRD measurements revealed that the sample posse...

several species of magnetotactic bacteria have been discovered recently. these bacteria synthesize intracellular magnetic nanoparticles in specific sizes and shapes and arrange them in chains. these particles called magnetosomes and can be used for drug-delivery, cell-targeting and hyperthermia. magnetotactic bacteria navigate along the magnetic field; this process is known as ‘magnetotaxis’ wh...