A 35-year-old pregnant woman visited our department and had been treated with 100 µg of daily oral levothyroxine for hypothyroidism. An ultrasonography screening was performed at 25 weeks gestation and revealed a fetal goiter and an increased amniotic fluid volume. Fetal hypothyroidism was confirmed by cordocentesis and amniotic hormone levels at 26 weeks gestation. We treated the mother with 2...

The antibodies responsible for haemolysis can be naturally occuring (eg, anti-A or anti-B antibodies) or can develop as a result of a sensitising event such as pregnancy or transfusion. The most well recognised is rhesus alloimmunisation (Greek: allo = 'other' or 'different from') which begins with red blood cells from a rhesus-positive fetus crossing the placental barrier during pregnancy and ...

constant venous flow. The waveforms were defined as abnormal if shifts in frequency at the end of diastole were absent in recordings obtained from three different points on the maternal abdomen. A sample offetal blood was taken from the umbilical vein by cordocentesis, and the oxygen tension and pH were determined (figure). The degree of fetal smallness was expressed as the number of standard d...

Thalassemia screening in pregnant women and their spouses was performed at Buddhachinaraj Provincial Hospital and 8 community hospitals in Phitsanulok; lower northern Thailand. The prevalence of thalassemic carrier state was determined of 1,198 couples. Of these, 4.8% had heterozygous alpha thalassemia-1, 1.6% had heterozygous beta thalassemia, 12.4% had heterozygous hemoglobin (Hb) E, 2.7% had...

BACKGROUND: Wolf-Hirschhorn syndrome is caused by distal deletion of the short arm of chromosome 4 (4p-). We report a case in which intrauterine growth restriction, hypospadias and foot deformity were detected by prenatal ultrasound examination at 29 weeks of gestation. CASE PRESENTATION: A 31-year-old gravida 2 partus 1 woman was referred at 29 weeks' gestation with suspicion of intrauterine g...

The effect of fetal anaemia on the total and differential leucocyte counts was studied by examining blood samples obtained by cordocentesis from 177 previously untransfused rhesus affected fetuses at 17-36 weeks' gestation. The mean fetal total leucocyte, lymphocyte, and monocyte counts were significantly lower than the corresponding values in normal controls and there were significant associat...

Comments Re a) After individual genetic counseling with regard to the risk of miscarriage caused by the invasive procedure and the risk of fetal chromosomal abnormality, every pregnant woman/couple decides whether an amniocentesis should be performed. From a strictly medical point of view, it is desirable that the risk of chromosomal abnormality be at least as high as that of miscarriage caused...

OBJECTIVE The objective of this study is to describe the effects of antepartum therapy for fetal alloimmune thrombocytopenia (FAIT) on lifestyle. With the goal of preventing intraventricular hemorrhage in all fetuses without cordocentesis to measure fetal platelets, empiric treatment with intravenous immune globulin (IVIG), with or without prednisone, is recommended. It is hypothesized that the...

Sequential control is a common control problem in industry. Despite its importance fairly little theoretical research has been devoted to this problem. We study a subclass of sequential control problems, which we call the SAS-PUBS class, and present a planning algorithm for this class. The algorithm is developed using formalism from artiicial intelligence (AI). For planning problems in the SAS-...