OBJECTIVE Corneal ulcers are commonly encountered in pinnipeds. Prolonged oral antibiotics and topical ophthalmic solutions may not be practical to administer, and novel treatment techniques are desired. Thermodynamic gels are a potential solution because they hold antimicrobials at the site of injection, slowly releasing drug. This study investigated the clinical efficacy of antibiotic-impregn...

The main objective of this study was to compare the physiological changes (withdrawal and corneal reflexes, respiratory and cardiac frequency, blood oxygen saturation, and rectal temperature) following intraperitoneal administration of ketamine (80 mg/kg) and xylazine (10 mg/kg) to 3-, 6-, 12- and 18-month-old male Sprague Dawley rats (n=6/age group). Plasma pharmacokinetics, liver metabolism, ...

PURPOSE The purpose of this study was to compare the level of patient pain during the phacoemulsification and implantation of foldable intraocular lenses while under topical, intracameral, or sub-Tenon lidocaine. PATIENTS AND METHODS This was a retrospective study. Three hundred and one eyes subjected to cataract surgery were included in this study. All eyes underwent phacoemulsification surg...

Purpose. To report a case of medication-resistant acanthamoeba keratitis (AK) treated successfully by corneal crosslinking (CXL). Methods. A 26-year-old male with medication-resistant AK underwent a standard CXL procedure with local anesthesia, followed by central corneal epithelial debridement, application of riboflavin 0.1%, and UV-A irradiation. Results. The patient experienced a dramatic sy...

A 25-week-old neonate was noted to have unilateral corneal edema and buphthalmos at birth following a forceps assisted delivery. Ten days later, examination of the neonate under anesthesia showed a central corneal perforation with a possible retinal detachment. By this time the neonate’s affected eye was deemed unsalvageable, and therefore an enucleation was performed with insertion of an ocula...

background: the effect of corticosteroid therapy on corneal wound healing is controversial. the objective of this study was to evaluate the effects of combination therapy with dexametha-sone and acetylcysteine at different times and durations on experimentally-induced corneal wounds and haze in rabbits. methods: eighteen adult new zealand white rabbits were divided into three groups of six each...

normal 0 false false false en-us x-none ar-sa background : the aim of this study was to determine the correlation between corneal hysteresis (ch) and the corneal resistance factor (crf), which are both novel methods of analyzing ocular rigidity/elasticity, and various corneal characteristics, mainly corneal volume in normal subjects. methods : this cross-sectional study included 500 normal eyes...

It has long been recognized that visual damage may follow the administration of anesthesia. In 1937, Guedel noted “We still see too much conjunctivitis and traumatic keratitis following anesthesia”1. The injuries at that time were attributed to open drop ether through a gauze covered mask in hard to handle subjects who half opened their eyes during light anesthesia (the patient was deemed in pa...

The local anesthetic activities of 1-(morpholino or piperidino)-2-propanol derivatives were investigated. These activities were observed with nerve trunk anesthesia, rabbit's corneal anesthesia and intradermal injection anesthesia. Among these propanol derivatives, No. 24 and No. 25 which possess thioether-type sulfur were the most active and the effective potency was enhanced by increasing the...