The aim of this study is to investigate the effects of non-Newtonian blood rheology models on the wall shear stress (WSS) distribution in a cohort of patients-specific coronary arteries. Twenty patients with diseased left anterior descending (LAD) coronary arteries (with varying degrees of stenosis severity from mild to severe) who underwent angiography and in-vivo pressure measurements were se...

this study evaluated the relationship between the location of the most severe coronary artery stenosis and the subsequent acute myocardial infarction (ami). methods: of 1590 patients who were admitted with a diagnosis of ami, we identified 44 patients who had undergone previous myocardial perfusion spect. thirty-one of these patients also had previous coronary angiography. the relationship betw...

Forty-nine patients have undergone combined aortic valve replacement and aortocoronary saphenous vein bypass graft surgery using a technique of distal coronary perfusion. Vein grafts are placed before replacement of the aortic valve, and continuously perfused by siting the proximal anastomoses high on the aortic root or individually perfusing the grafts before proximal anastomosis. Continuous c...

Case presentation A: A 50-year-old diabetic man presented to the hospital after 8 hours of continuous chest pain. Because of acute myocardial infarction of the anterior wall, he underwent direct stenting to an occlusion in the left anterior descending coronary artery. Despite revascularization, suboptimal coronary flow was achieved, and he subsequently developed heart failure. Case presentation...

background: more diagnostic techniques require a better understanding of the forces and stresses developed in the wall of the left ventricle. the aim of this study was to differentiate significant coronary artery disease (cad) patients using a non-invasive quantification of myocardial wall stress in the diastole phase. methods: sixty male subjects with sinus rhythm (30 patients with significant...

Abstract Familial hypercholesterolemia (FH) is a hereditary dislipidemia. Patients present with extremely high level of low-density lipoprotein cholesterol (LDL-C), which is due to mutation in the gene of LDL receptor. Homozygous patients (HoFH) whose incidence is 1 in 1.000.000 are at high risk of premature aortic valve stenosis, and coronary artery atherosclerosis. In homozygous individual...

PREVIOUS investigations in animals have shown the relative importance of the various components of cardiac effort: heartrate,l 2 arterial pressure,3 " cardiac output,3-5 rate of pressure development,7-'8 and the "tension-time index"9 as hemodynamic determinants of coronary blood flow and myocardial oxygen consumption. Particular emphasis has been placed on the importance of arterial pressure an...

THE presence of angina in patients scheduled for nonCase 1 cardiac surgery is considered a risk factor for perioperative cardiovascular complications. Myocardial revascularization is an effective treatment for angina; when performed before noncardiac surgery, it decreases cardiac complications compared with medical therapy.223 Patients who undergo myocardial revascularization with internal mamm...