Objectives At the conclusion of this program, participants should be able to: 1. Identify the typical features of migraine aura. 2. Describe the pathophysiologic mechanisms behind migraine aura. 3. Correlate the physiology of cortical spreading depression to the clinical phenomena of migraine aura. 1. Migraine aura is associated with which of the following conditions: a. Cortical spreading depr...

Autoimmune diseases are typically characterized by a persistent inflammatory self-recognition process that ultimately leads to chronic progressive disability. Over the past several years we have addressed the fundamental question of why autoimmune diseases are chronic. Our working hypothesis in these studies has been that autoimmunity involves a continuous acquisition of new self-recognition ev...

After compensation, the measurement errors arising from multiple fluorescences spilling into each detector become evident by the spreading of nominally negative distributions. Depending on the instrument configuration and performance, and reagents used, this "spillover spreading" (SS) affects sensitivity in any given parameter. The degree of SS had been predicted theoretically to increase with ...

We present a new model of turbulence spreading in magnetically confined plasma. A basic question in turbulence spreading is how to sustain finite amplitude fluctuations in a stable subcritical region, where linear dissipation of the turbulence is strong? The answer to this question relies on a consistent treatment of mesoscale temperature profile corrugation and microscale turbulence. We argue ...

The timing of pedal depressions and releases was measured relative to key depressions and releases in two pianists' performances of Robert Schumann's "Traumerei" on an electronic instrument. Each pianist provided 9 complete performances, 3 at each of 3 tempi, which were analyzed by examining in detail those positions in the music in which the pedal was used consistently. The principal questions...

It is well-known that children, unlike adults, would frequently give a no-answer to questions like those in (1) and (2) if they are presented without overt linguistic context, but become significantly more successful if the stimuli are presented in a context enriched (or otherwise manipulated) in various ways (Crain et al. 1996, Philip and Lynch 2000, Drozd and van Loosbroek 1998, Sugisaki and ...