Non-aqueous system are well known as solvent or drug suspension vehicles and oleogels micro emulsion with no aqueous phase (anhydrous, non-aqueous oil-in-oil emulsion) have had relatively scant attention yet may have uses as drug reservoir as well as template for the preparation of microemulsion combination with a cosurfactant. Microemulsions have emerged as novel vehicles for drug delivery whi...

The aim of this study is to develop a microemulsion product from a plant essential oil having the highest anti-tyrosinase activity. The in vitro anti-tyrosinase activity of six essential oils extracted from six edible plants was compared. The oil of Cymbopogon citratus demonstrated the highest activity which was significantly nontoxic to normal human cells. The GC-MS data indicated that gerania...

In this work, we report on the synthesis of superparamagnetic iron oxide nanoparticles at room temperature using microemulsion template phase consisting of cyclohexane, water, CTAB as cationic surfactant and butanol as a cosurfactant. Surface modification have been carried out by using poly(ethyleneglycol) (PEG). The structure,morphology, and magnetic properties of the products were characteriz...

In this work, we report on the synthesis of superparamagnetic iron oxide nanoparticles at room temperature using microemulsion template phase consisting of cyclohexane, water, CTAB as cationic surfactant and butanol as a cosurfactant. Surface modification have been carried out by using poly(ethyleneglycol) (PEG). The structure,morphology, and magnetic properties of the products were characteriz...

In this work, we report synthesis of superparamagnetic iron oxide nanoparticles at room temperature using microemulsion template phase consisting of cyclohexane, water, cetyltrimethylammonium bromide CTAB as cationic surfactant and butanol as a cosurfactant. Silica surface modification of the as prepared nanoparticles was performed by adding tetraethoxysilane TEOS to alkaline medium. The struct...

Objective: In current research, solid lipid nanoparticles (SLN) are formulated for the anticancer drug, nilotinib, to conquer drawbacks associated with drug including low bioavailability and solubility. Methods: The formulation comprised of tripalmitin (lipid), poloxamer 188(surfactant) glyceryl palmitostearate (cosurfactant) by solvent evaporation technique. process variables SLN were optimize...

results the results showed that the maximum oil was incorporated in microemulsion system that contained surfactant to cosurfactant ratio of 4:1. the mean droplet size range of microemulsion formulation was in the range of 5.09 to 159 nm, and its refractory index (ri) and ph were 1.44 and 7, respectively. viscosity range was 57-226 cps. drug release profile showed that 48.18% of the drug release...

the objectives of present investigations were to optimize concentration of oil, surfactant and cosurfactant by pseudoternary phase diagrams and to develop a stable formulation of self emulsifying drug delivery system (sedds) in order to enhance the dissolution rate of poorly soluble irbesartan (ibs) by sedds. pseudoternary phase diagrams were constructed to identify the self emulsifying region....

An equilibrium phase belonging to the family of bilayer liposomes in ternary mixtures of dimyristoylphosphatidylcholine (DMPC), water, and geraniol (a biological alcohol derived from oil-soluble vitamins that acts as a cosurfactant) has been identified. Electron and optical microscopy reveal the phase, labeled Ltv, to be composed of highly entangled tubular vesicles. In situ x-ray diffraction c...

Insulin-loaded microemulsions for transdermal delivery were developed using isopropyl myristate or oleic acid as the oil phase, Tween 80 as the surfactant, and isopropyl alcohol as the cosurfactant. The pseudoternary phase diagrams were constructed to determine the composition of microemulsions. The insulin permeation flux of microemulsions containing oleic acid as oil phase through excised mou...