Cortex Phellodendri amurensis (CPA), derived from the dried bark of Phellodendron amurense Rupr., is a traditional medicine widely used to treat various inflammation-related diseases. The aim of this study was to investigate the anti-inflammatory activity and molecular mechanism of CPA in vivo and in vitro. Mice were pretreated with CPA (200 mg/kg, p.o.) for three consecutive days; 2h after the...

Chronic pulmonary aspergillosis (CPA) may complicate pulmonary sarcoidosis. We re-estimated the global burden of sarcoidosis and the burden of CPA complicating sarcoidosis. We searched the literature and reference lists of retrieved papers to identify all published sarcoidosis incidence and prevalence data. We estimated the frequency of CPA from 11 papers relating to >3,000 patients with sarcoi...

This case report illustrates the potential fallacy of attributing a patient's symptoms to an incidental finding. Serial imaging of small, asymptomatic cerebellopontine angle (CPA) lipomas is favored. It is imperative to accurately diagnose CPA lipoma on imaging and differentiate it from more common CPA lesions. We herein present a patient with symptoms consistent with Bell's palsy and an incide...

Precise type information is invaluable for analysis and optimization of object-oriented programs. Some forms of polymorphism found in object-oriented languages pose significant difficulty for type inference, in particular data polymorphism. Agesen’s Cartesian Product Algorithm (CPA) can analyze programs with parametric polymorphism in a reasonably precise and efficient manner, but CPA loses pre...

Microparticle and nanoparticle formulations are widely used to improve the bioavailability of low-solubility drugs and as vehicles for organ- and tissue-specific targeted drug delivery. We investigated the effect of a novel, controlled-release form of a bioactive lipid, cyclic phosphatidic acid (cPA), on human colon cancer cell line functions. We encapsulated cPA in gelatin-based hydrogels and ...

Background Hemangioblastomas are the most common primary tumor of the posterior fossa. There are few cases of hemangioblastoma of the cerebellopontine angle (CPA). When present in this location, hemangioblastoma presents a diagnostic challenge as its imaging findings closely resemble those of vestibular schwannoma (VS), which is much more common in the CPA. Case Description We report the case...

Consider Pr [ A( ,Uk,·) ( 1, E ( 1,Uk,m k )) = 1 ] for b = 0, 1 (we will refer to this as Pr [A0] and Pr [A1] for convenience). Suppose that the oracle is queried at most p (k) times for some polynomial p (k). The i-th time the oracle is queried, it picks some random c0 (call it ci,0) and then returns ci,0,Uk (ci,0) ⊕m. Let E be the event that ci,0 = c 0 for any i. Since each ci,0 is chosen at ...

BACKGROUND The aim of this study was to compare the diagnostic performances of the collagen proportionate area (CPA) and liver stiffness measurement (LSM) for liver fibrosis quantification in chronic hepatitis C (CHC). METHODS A total of 137 eligible consecutive Taiwanese patients (74 women and 63 men; age 21-80 years; median age 54 years), with CHC underwent LSM by using acoustic radiation f...

The effects of cyclopiazonic acid (CPA), a known Ca2'-pump inhibitor at internal stores, were investigated on electrical responses of the membrane of smooth muscle cells in small segments (O.3-O.5 mm long) of circular smooth muscle isolated from the guineapig gastric antrum. In most preparations, the membrane was spontaneously active with the generation of unitary potentials and regenerative sl...