Background Oral creatine supplementation is known to provide numerous benefits, including increases in lean muscle mass, muscular strength, and enhanced performance in various athletic capacities. The creatine transporter is a transmembrane protein that mediates the entry of creatine from the circulation into the muscle cell. Little is understood about the importance of the creatine transporter...

In recent years, the practice of bodybuilding has seen an increase in number fans gyms and, along with this increase, use dietary supplements, such as creatine and whey protein, been growing considerably by practitioners sport. addition, daily protein intake bodybuilders exceeds maximum recommendation, which, together these can lead to kidney and/or liver failure. The objective study was analyz...

background: the aim of the present study was to investigate the in vitro effects of mercury (hg+2), lead (pb+2), silver (ag+2), tin (sn+2), bismuth (bi+3) and indium (in+3) ions on sperm creatine kinase. methods: creatine kinase was isolated from human sperm homogenates after chromatography on a deae cellulose column. results: at 60 µg ml-1 metal concentration, 70% of the creatine kinase activi...

the purpose of this investigation was to develop a simple colorimetric method for creatine kinase (ck). the new method is based on the reaction of creatine, formed enzymatically from creatine phosphate and adp, with different glyoxal compounds. hydrated glyoxals, such as para-nitrophenyl, 2-thiophene, 4- biphenyl, 4, 4' -biphenyl,α-naphthyl, β-naphthyl, para-chlorophenyl, and styryl were s...

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background delayed onset muscle soreness (doms) is the sensation of stiffness and pain in the muscles that occurs 24-48 hours after unaccustomed or strenuous exercise. objectives the aim of this study was to examine and compare the effect of vibration training (vt) on delayed onset muscle soreness. materials and methods twenty healthy non-athletic volunteers (female, age 20-30 years, body mass ...

OBJECTIVE To assess the diagnostic value at admission of creatine kinase MB mass concentration, alone or in combination with electrocardiographic changes, in suspected myocardial infarction. DESIGN Prospective study of all consecutive patients admitted within 12 hours after onset of chest pain to a coronary care unit for evaluation of suspected myocardial infarction. SETTING Large regional ...

Mitochondria from transgenic mice, expressing enzymatically active mitochondrial creatine kinase in liver, were analyzed for opening of the permeability transition pore in the absence and presence of creatine kinase substrates but with no external adenine nucleotides added. In mitochondria from these transgenic mice, cyclosporin A-inhibited pore opening was delayed by creatine or cyclocreatine ...