PURPOSE We examined the effects of creatine supplementation on the response to repeated bouts of resistance exercise. METHODS Young men (24.1 ± 5.2 yr) were divided into Creatine (CM, n = 9) and Placebo (PL, n = 9) groups. On day (D) 1 and D15, subjects performed four sets of bicep curls at 75% 1-RM to concentric failure. On D8-D13, subjects consumed either 20g/d creatine monohydrate or place...

BACKGROUND The effects of creatine on brain metabolism and the potential cognitive enhancing properties of this compound raise the possibility of developing a new augmentation therapeutic strategy in schizophrenia especially in patients demonstrating negative and cognitive symptomatology. METHODS Seven inpatients with chronic schizophrenia presenting with treatment resistant negative symptoms...

Background It has previously been shown that the plasma concentration of creatine following supplementation is influenced by extracellular concentrations of insulin and glucose, the form in which creatine is administered, and also the creatine concentration in the muscle cells. The common practice of raising insulin levels to increase initial uptake into muscle, by means of high amounts of gluc...

Background Creatine monohydrate is known to prolong time to fatigue and training volume during resistance training while ingestion of whey protein in the post-exercise window is critical to maximize adaptations. Individually, research supports that both creatine and whey protein ingestion ultimately leads to increased strength gains and improved body composition. Research is well supported and ...

Creatine monohydrate has become one of the most popular ergogenic sport supplements used today. It is a nonessential dietary compound that is both endogenously synthesized and naturally ingested through diet. Creatine ingested through supplementation has been observed to be absorbed into the muscle exclusively by means of a creatine transporter, CreaT1. The major rationale of creatine supplemen...

Creatine monohydrate is a popular sports supplement used to maintain levels of high-energy phosphates during exercise. As a supplement, varying amounts are consumed per person corresponding to parameters such as body mass and level of training (i.e. maintenance versus loading doses). Numerous studies have reported beneficial effects including increased muscle mass during training and neural pro...

background and aim: creatine is an energy-supplying protein in neuromuscular system with a protective role in relieving neurological symptoms. since the enzymes and other mechanism involved in the conversion of creatine in the inner ear and vestibular nuclei are found in abundance, the aim of this study was to measure the effects of creatine on cervical vestibular evoked myogenic potentials (cv...

BACKGROUND Creatine monohydrate (CrM) has been consistently reported to increase muscle creatine content and improve high-intensity exercise capacity. However, a number of different forms of creatine have been purported to be more efficacious than CrM. The purpose of this study was to determine if a buffered creatine monohydrate (KA) that has been purported to promote greater creatine retention...

We hypothesized that increasing skeletal muscle total creatine (Cr) content through dietary Cr supplementation would result in slower muscle phosphocreatine concentration ([PCr]) kinetics, as assessed using (31)P magnetic resonance spectroscopy, following the onset and offset of both moderate-intensity (Mod) and heavy-intensity (Hvy) exercise. Seven healthy males (age 29 +/- 6 yr, mean +/- SD) ...