The present study attempts to elucidate the anti-osteoporotic activity of Artemisia capillaris Thunb. in the form of anti-osteoclastic effect and responsible bioactive compounds. The contents of chlorogenic acid, caffeic acid, hyperoside, isoquercitrin, isochlorogenic acid A, and scoparone in Artemisia capillaris hydroethanolic extract (ACHE) were 38.53, 0.52, 4.07, 3.03, 13.90, and 6.59 mg/g, ...

From the roots of Crepis conyzifolia, two new and two known guaianolides were isolated together with three known phenylpropanoids. Structures of the new compounds were established as 8beta-hydroxy-4beta, 15-dihydrozaluzanin C and 4beta, 15, 11beta, 13-tetrahydrozaluzanin C-3-O-beta-glucopyranoside by spectral methods. The identity of 8-epiisolippidiol and dentalactone was also discussed.

In contrast to the huge variety of sesquiterpene lactones reported, only a limited number of flavonoids and phenolic acids are known from the genus Crepis. Compounds detected in the course of this investigation encompass flavonoids luteolin, luteolin 7-O-glucoside, luteolin 7-O-gentiobioside, luteolin 7-Oglucuronide, and luteolin 4’-O-glucoside and caffeic acid derivatives chlorogenic acid, 3,5...

objective(s): to study the c-kit expression in the gallbladder of cholesterol lithogenic guinea pig model and the effect of artemisia capillaris thunb on interstitial cells of cajal (iccs). materials and methods:a total of 45 guinea pigs were randomly assigned into three groups: the control group (guinea pigs fed a standard diet, normal group); the model group (guinea pigs fed a cholesterol gal...

In our screening program for new agrochemicals from local wild plants, Artemisia capillaris and A. mongolica were found to possess insecticidal activity against the maize weevil, Sitophilus zeamais. The essential oils of aerial parts of the two plants were obtained by hydrodistillation and were investigated by GC and GC-MS. The main components of A. capillaris essential oil were 1,8-cineole (13...

The host immune system is the first line of host defense, consisting mainly of innate and adaptive immunity. Immunity must be maintained, orchestrated, and harmonized, since overactivation of immune responses can lead to inflammation and autoimmune diseases, while immune deficiency can lead to infectious diseases. We investigated the regulation of innate and adaptive immune cell activation by A...

OBJECTIVES To study the c-Kit expression in the gallbladder of cholesterol lithogenic guinea pig model and the effect of Artemisia capillaris Thunb on interstitial cells of Cajal (ICCs). MATERIALS AND METHODS A total of 45 guinea pigs were randomly assigned into three groups: the control group (guinea pigs fed a standard diet, normal group); the model group (guinea pigs fed a cholesterol gall...

Plant extracts have been used as herbal medicines to treat a wide variety of human diseases. We used response surface methodology (RSM) to optimize the Artemisia capillaris Thunb. extraction parameters (extraction temperature, extraction time, and ethanol concentration) for obtaining an extract with high anti-inflammatory activity at the cellular level. The optimum ranges for the extraction par...

The seed oil of Crepis eonyzaefolia (Gouan) Daile Torre contains previously unidentified (± )-eis-12,13epoxyoctadeca-trans-6-cis-9-dienoic (14 and eis-12,13-epoxyoctadeca-cis-6-cis-9-dienoic (2 ~{) acids and the more common vernolic [( ±)-12,13-epoxyoctadec-cis-9-enoic] (32 %) acid.

This study evaluated the in vitro effect of medicinal plant extracts on ruminal methanogenesis, four different groups of methanogens and ruminal fermentation characteristics. A fistulated Holstein cow was used as a donor of rumen fluid. Licorice and mugwort extracts (Glycyrrhiza uralensis and Artemisia capillaris, 0.5% and 1% of total substrate DM, respectively), previously used as folk remedie...