نتایج جستجو برای: crohns disease
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Crohns disease is characterized by chronic intestinal inflammation and not rarely by extraintestinal manifestations. Psoas abscess and fistula is a rare complication of Crohns disease, which is sometimes difficult to diagnose in the early stage. We describe the case of a 22-year-old male patient with Crohns disease who presented to us with difficulty in walking and pain in the area of the ri...
Alopecia areata (AA) is a non-scaring alopecia in which the characteristic initial lesion is a circumscribed totally bald, smooth patch. The term alopecia universalis is applied to total or amost total loss of all body hair. A 48-year old man presented with a two-month history of diarrhea and a twoweek history of low-grade fever. Patient was diagnosed twelve years ago with AA universalis treate...
BACKGROUND Development of inflammatory bowel disease (IBD) involves the interplay of environmental and genetic factors with the host immune system. Mechanisms contributing to immune dysregulation in IBD are not fully defined. Development of novel therapeutic strategies is focused on controlling aberrant immune response in IBD. Current IBD therapy utilizes a combination of immunomodulators and b...
The epoxygenase CYP2J2 has an emerging role in inflammation and vascular biology. The role of CYP2J2 in phagocytosis is not known and its regulation in human inflammatory diseases is poorly understood. Here we investigated the role of CYP2J2 in bacterial phagocytosis and its expression in monocytes from healthy controls and Crohns disease patients. CYP2J2 is anti-inflammatory in human periphera...
BACKGROUND In Crohn's disease high tissue expression and serum levels of chemokines and their receptors are known to correlate with disease activity. Because statins can reduce chemokine expression in patients with coronary diseases, we wanted to test whether this can be achieved in patients with Crohn's disease. METHODOLOGY/PRINCIPAL FINDINGS We investigated plasma levels of chemokines (CCL2...
Abstract Peritoneal Tuberculosis (PTB) is a rare extra-pulmonary manifestation of Mycobacterium tuberculosis infection. It usually presents with non-specific symptoms that can mimic other intra-abdominal pathology. Therefore, high index suspicion needed for diagnosis and early treatment PTB. Some the conditions in young patients may have similar presentations to PTB include Crohns’ disease, ova...
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