BACKGROUND Measuring C-reactive protein (CRP) has been recommended to identify patients at high risk for coronary heart disease (CHD) with low LDL cholesterol (LDL-C). Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a proinflammatory enzyme associated primarily with LDL. METHODS AND RESULTS In a prospective, case cohort study in 12 819 apparently healthy middle-aged men and women in the ...

BACKGROUND Measurement of C-reactive protein (CRP) is used for diagnosing and monitoring systemic inflammatory disease in canine patients. An automated human immunoturbidimetric assay has been validated for measuring canine CRP, but cross-reactivity with canine CRP is unpredictable. OBJECTIVE The purpose of the study was to validate a new automated canine-specific immunoturbidimetric CRP meth...

BACKGROUND Accelerated arteriosclerosis with cardiovascular disease is the main cause of death in end-stage renal disease patients. Increased, levels of C-reactive protein (CRP) and evidence of chronic Chlamydia pneumoniae infection have been identified as risk factors for cardiovascular disease in the general population. We tested the hypothesis that elevation of CRP, indicating chronic inflam...

INTRODUCTION Both converted and difficult laparoscopic cholecystectomies (LC) have impact on operating time and training of juniors. The aim of this study is to evaluate parameters that predict difficult LC or conversion (C), and find predictive values for different cut-off points of C-reactive protein (CRP) for conversion. MATERIALS AND METHODS A retrospective cohort study of cholecystectomi...

C-reactive protein (CRP) 1 is an acute phase serum protein produced rapidly in response to inflammatory stimuli. The binding and functional characteristics of CRP suggest that it may play a role in host defense against infection. CRP has binding specificity for the phosphocholine (PC) determinant of cell wall C-polysaccharide (PnC) from Streptococcus pneumoniae (1, 2). The binding of CRP to PnC...

C-reactive protein (CRP) 1 is an acute phase serum protein produced rapidly in response to inflammatory stimuli. The binding and functional characteristics of CRP suggest that it may play a role in host defense against infection. CRP has binding specificity for the phosphocholine (PC) determinant of cell wall C-polysaccharide (PnC) from Streptococcus pneumoniae (1, 2). The binding of CRP to PnC...