BACKGROUND Cryotherapy is a relatively novel ablation modality for the endoscopic ablation of Barrett's esophagus (BE). Data on the use of pressurized carbon dioxide (CO2) gas for cryoablation are scarce. STUDY AIM To determine the efficacy and safety of cryospray ablation using pressurized CO2 gas in the treatment of BE with early neoplasia. METHODS In this prospective single center case s...

The goal of catheter ablation is to create lesions that would cause local tissue destruction and thus eliminate or modify arrhythmia substrate. This is commonly accomplished by changing cellular temperature at two extremes by either heating or cooling with radiofrequency (RF) and cryothermal energy respectively. Both RF and cryoablation technologies are widely available. It is because of the “c...

Introduction. The purpose of this study was to evaluate the role of renal cryoablation in patients with solitary kidneys with the goals of tumor destruction and maximal renal parenchymal preservation. Methods. Eleven patients with single tumors were treated with cryoablation, of which 10 patients had solitary kidneys and 1 had a nonfunctioning contralateral kidney. All procedures were performed...

BACKGROUND The efficacy of transcatheter cryoablation for ventricular tachycardia (VT) remains controversial because of the limited size of the lesion produced. An increased lesion size if the cryoablation catheter profile and catheter tip length were increased was hypothesized. METHODS AND RESULTS Closed-chest transcatheter cryoablation was applied with 7F, 6-mm tip (n=11, 7F group) and 9F, ...

OBJECTIVE To explore the mechanism and significance of tumor angiogenesis by observing changes of micro-vessel density (MVD) and expression of vascular endothelial growth factor (VEGF) in residual tumor tissues after cryoablation. MATERIALS AND METHODS A total of 18 nude mice xenograft models with transplanted lung adenocarcinoma cell line A549 were established and randomly divided into 3 gro...

Worldwide, lung cancer is the most commonly diagnosed cancer, and lobectomy is the gold-standard treatment for early-stage non-small cell lung cancer (NSCLC). However, many patients are poor surgical candidates for various reasons. Recently, image-guided ablation is being used for lung tumors. Cryoablation has been applied for the treatment of cancer in various nonaerated organs; recently it ha...

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OBJECTIVES To assess the effects of intraoperative left atrial epicardial cryoablation on rhythm and atrial and ventricular function. DESIGN Thirty five patients with coronary artery disease and documented atrial fibrillation underwent coronary artery bypass surgery and concomitant cryoablation. An age and gender matched control group of 35 patients with atrial fibrillation underwent bypass s...

PURPOSE Preservation of renal function is of paramount importance in patients with tumors in solitary kidneys. We compared the renal function and oncologic outcomes of patients treated by partial nephrectomy with those of patients treated by cryoablation for solitary kidney tumors. MATERIALS AND METHODS All patients with solitary kidneys who were treated for renal tumors at our institution be...

INTRODUCTION The objective of our study is to present the first Brazilian cryoablation experience in the treatment of low and intermediate risk localized prostate cancer using 3rd generation cryoablation and real-time biplanar transrectal ultrasonography. MATERIALS AND METHODS Ten Brazilian patients underwent primary cryoablation for localized prostate cancer between October 2010 and June 201...