A 39-year-old man presented with a rapidly growing unilateral painless nodule on the right cheek. Histopathological examination and peripheral blood analysis both showed a population of T-cell large granular lymphocytes, which were CD1+, CD2+, CD5+, CD7+ and CD16+, with expression of cutaneous lymphocyte-associated antigen. Further laboratory examination revealed severe neutropaenia, relative l...

INTRODUCTION Cutaneous metastases in the facial region occur in less than 0.5% of patients with metastatic cancer. They are an important finding and are not often the first sign leading to diagnosis. CASE PRESENTATION We describe the case of a 64-year-old male patient who presented with dyspnea, pleuritic pain, loss of weight and a nodule on his left cheek. A chest X-ray revealed a left upper...

© 2012 The Authors. doi: 10.2340/00015555-1450 Journal Compilation © 2012 Acta Dermato-Venereologica. ISSN 0001-5555 Skin metastasis of ovarian carcinoma is rare (1). Some cases show umbilical metastasis, known as Sister Mary Joseph’s nodule (2). Other cutaneous metastases of ovarian carcinoma include pilomatricoma-like (3) and cauliflower-type (4) variants. Only one case of nodular cutaneous m...

Pancreatic cancer is one of the most dangerous human cancers and will continue to be a major unsolved health problem as we enter the 21(st) century. This is the case despite advances in imaging technology and surgical management. Indeed, 80% to 90% of pancreatic cancers are diagnosed either at the locally advanced or metastatic stage. Cutaneous metastases originating from pancreatic cancer are ...

granular cell tumors are rare neoplasms of uncertain histogenesis but with a typical histologic appearance composed of cells with characteristic granular cytoplasm. these tumors occur most often in adults as an asymptomatic solitary papule or nodule. multiple granular cell tumors are rare, especially in children and teenagers. we represent a case of multiple granular cell tumors in a 19-year-ol...

A 43-year-old middle-eastern woman was visited with a 15-year history of multiple painful cutaneous nodules on her back. The first lesion appeared on her back when she was 28 years old. As she aged, the lesions became larger, more numerous, and more painful with cold or physical contact. Her medical history was not significant. The patient’s medications included naproxen, calcium-D, and vitamin...

Heel pain is a common presentation in outpatient clinics. Here, we report a 69-year-old woman who complaint about a painful nodule on her left posterior heel. There was no history of trauma. The lesion developed during ten weeks without any bleeding or ulceration. On examination, we observed a subcutaneous firm nodule of about 1 cm in diameter. The lesion was hypoechoic in diagnostic sonography...