The objective of this study was to examine the effects of cyclic compressive loading on chondrogenic differentiation of rabbit bone-marrow mesenchymal stem cells (BM-MSCs) in agarose cultures. Rabbit BM-MSCs were obtained from the tibias and femurs of New Zealand white rabbits. After the chondrogenic potential of BM-MSCs was verified by pellet cultures, cell-agarose constructs were made by susp...

Considering economical reasons and attempting to reduce carbon foot print of concrete structures, there is increasing tendency toward use of high strength reinforcement in seismically active regions. ACI 318-19, Iranian steel rebars standard INSO 3132 and next edition of Iranian national building allow the use of high strength rebars in elements of ductile force resisting systems. Therefore it ...

The response analysis of reinforced concrete (RC) structures subjected to strong earthquake motions requires material models that are able to simulate cyclic deformation and damage realistically. This paper presents the results of a study of pinching and softening behaviour in an RC frame subjected to cyclic loading. The experiment was conducted on a full-scale RC frame at Indian Institute of T...

This article presents the strain-based experimental data for Ti-6Al-4V ELI under non-constant amplitude cyclic loading. Uniaxial strain-controlled fatigue experiments were conducted under three different loading conditions, including two-level block loading (i.e. high-low and low-high), periodic overload, and variable amplitude loading. Tests were performed under fully-reversed, and mean strain...

OBJECTIVES Secondary caries is the most common reason for composite restoration replacement and usually forms between dentin and the filling. The objective of this study was to investigate the combined effect of cyclic loading and bacterial exposure on bacterial penetration into gaps at the interface between dentin and resin composite restorative material using a novel bioreactor system and tes...

A framework for development of constitutive models based on semi-micromechanical aspects of plasticity is proposed. The resulting of this model for material employed friction type failure criterion, sub-loading surface, and associated flow rule. This model is capable of predicting effects of the rotation of principal stress/strain axes and consequent plastic flow, induced anisotropy of strength...

During earthquake excitations, reinforced concrete bridge columns can be subjected to a combination of axial load, shear force, flexural moments, and torsional moments. The torsional moment can be much more significant in columns of bridges that are skewed, curved, have unequal spans, or unequal column heights. Combined loading including torsion can result in complex flexural and shear failure ...

During an earthquake, structures are subjected to both horizontal and vertical shaking. Most structures are rather insensitive to variations in the vertical acceleration history and primary considerations are given to the impact of the horizontal shaking on the behavior of structures. In the laboratory, however, most component tests are carried out under uni-directional horizontal loading to si...

Repetitive lifting in the workplace has been identified to be a cause of low back disorders. Epidemiologic data further supports an hypothesis that higher repetition rate (i.e. frequency) is an added risk factor. The objective of this study was to provide experimental data testing the above hypothesis. An in vivo feline model was subjected to 20-min of cyclic lumbar loading at frequencies of 0....

Offshore wind turbine (OWT) foundations are subjected to a combination of cyclic and dynamic loading arising from wind, wave, rotor and blade shadowing. Under cyclic loading, most soils change their characteristics including stiffness, which may cause the system natural frequency to approach the loading frequency and lead to unplanned resonance and system damage or even collapse. To investigate...