Assume a diploid species consisting of an infinite number of competing demes, each having N(e) reproducing members and in which mating is at random. Then consider a locus at which a pair of alleles A and A' are segregating, where A' is the "altruistic allele," which has selective disadvantage s' relative to A with respect to individual selection, but which is beneficial for a deme in competitio...

let $a$ be an arbitrary banach algebra and $varphi$ a homomorphism from $a$ onto $bbb c$. our first purpose in this paper is to give some equivalent conditions under which guarantees a $varphi$-mean of norm one. then we find some conditions under which there exists a $varphi$-mean in the weak$^*$ cluster of ${ain a; |a|=varphi(a)=1}$ in $a^{**}$.

Phosphatidylinositol 3-kinase (PI3-kinase) activates protein kinase B (also known as Akt), which phosphorylates and activates a cyclic nucleotide phosphodiesterase 3B. Increases in cyclic nucleotide concentrations inhibit agonist-induced contraction of vascular smooth muscle. Thus we hypothesized that the PI3-kinase/Akt pathway may regulate vascular smooth muscle tone. In unstimulated, intact b...

1. The contractile response to nitric oxide (NO) in ral ileal myenteric plexus-longitudinal muscle strips was pharmacologically analysed. 2. NO (10(-7) M) induced only contraction while 10(-6) M NO induced contraction followed by relaxation. Methylene blue (up to 10(-4) M) did not affect the NO-induced contractions but significantly reduced the relaxation evoked by 10(-6) M NO. Administration o...

The effects of tiropramide hydrochloride on Ca(2+)-induced contraction, cytoplasmic free Ca2+ levels and tissue cyclic AMP concentrations were investigated to elucidate the mechanisms of its antispasmodic action in the isolated detrusor from rats. Tiropramide inhibited the Ca2+ (3 mM)-induced contractions of the isolated urinary bladder depolarized in a Ca(2+)-free medium, and the IC50 value wa...

background: surface electromyography (semg) of muscles is a non-invasive tool that can be helpful in the assessment of muscle function and some motor control evaluations. a loss of force, known as muscle fatigue is accompanied by changes in muscle electrical activity. one of the most commonly used surface emg parameters which reflects paraspinal muscle fatigue during different tasks and positio...

In this paper we prove that every n-Jordan homomorphis varphi:mathcal {A} longrightarrowmathcal {B} from unital Banach algebras mathcal {A} into varphi -commutative Banach algebra mathcal {B} satisfiying the condition varphi (x^2)=0 Longrightarrow varphi (x)=0, xin mathcal {A}, is an n-homomorphism. In this paper we prove that every n-Jordan homomorphism varphi:mathcal {A} longrightarrowmathcal...

Let $A$ be an arbitrary Banach algebra and $varphi$ a homomorphism from $A$ onto $Bbb C$. Our first purpose in this paper is to give some equivalent conditions under which guarantees a $varphi$-mean of norm one. Then we find some conditions under which there exists a $varphi$-mean in the weak$^*$ cluster of ${ain A; |a|=varphi(a)=1}$ in $A^{**}$.

The B domain of staphylococcal protein A (BdpA) is a small helical protein that has been studied intensively in kinetics experiments and detailed computer simulations that include explicit water. The simulations indicate that BdpA needs to reorganize in crossing the transition barrier to facilitate folding its C-terminal helix (H3) onto the nucleus formed from helices H1 and H2. This process su...