BACKGROUND There is appreciable utilisation of antihistamines (H1) in European countries, either prescribed by physician and purchased by patients for self-medication. Terfenadine and astemizole underwent regulatory restrictions in '90 because of their cardiac toxicity, but only scarce clinical data are available on other antihistamines. AIM To investigate the pro-arrhythmic potential of anti...

There are three categories ofmedicine in terms of their availability to the public; (a) prescription only (POM), which can only be obtained on a medical or dental prescription; (b) pharmacy only (P), which do not require such a prescription, but can only be purchased in a pharmacy under the supervision of a registered pharmacist; and (c) medicines on the General Sales List, which are available,...