Modification of peptide sequence offers versatile control over their self-organization capability within adlayers adsorbed on surfaces. However, to gain full the self-organization, clear links between and lateral ordering in these must be established. Using molecular dynamics simulations WA or AW dipeptides, spontaneous emergence ordered nano-patterns containing neutral, zwitterion, neutral-zwi...

we show  that a projective maximal submodule of afinitely generated, regular, extending module is a directsummand. hence, every finitely generated, regular, extendingmodule with projective maximal submodules is semisimple. as aconsequence, we observe that every regular, hereditary, extendingmodule is semisimple. this generalizes and simplifies a result of  dung and   smith. as another consequen...

Submit Manuscript | http://medcraveonline.com Abbreviations: AD: Alzheimer Disease; Apo-E: ApoLipoprotein-E; BBB: Blood Brain Barrier; Brainpeps: BBB Peptide Database; CNS: Central Nervous System; CSF: CerebroSpinal Fluid; EPIC: Engineered Peptide Compound; HAD: HIVAssociated Dementia; HIFU: High Intensity Focused Ultrasound; HIV: HIV Encephalitis; HIV: Human Immunodeficiency Virus; LPR: Lipopr...

A simple and reproducible water-in-oil (W/O) nanoemulsion technique for making ultrasmall (<15 nm), monodispersed and water-dispersible nanoparticles (NPs) from chitosan (CS) is reported. The nano-sized (50 nm) water pools of the W/O nanoemulsion serve as "nano-containers and nano-reactors". The entrapped polymer chains of CS inside these "nano-reactors" are covalently cross-linked with the cha...

In this tutorial review the process and applications of peptide self-assembly into nanotubes, nanospheres, nanofibrils, nanotapes, and other ordered structures at the nano-scale are discussed. The formation of well-ordered nanostructures by a process of self-association represents the essence of modern nanotechnology. Such self-assembled structures can be formed by a variety of building blocks,...

The influence of secretin (10(-10) - 10(-8) M), a gastrointestinal hormone, on the relaxing response of rat thoracic aorta rings preconstricted by 40 mM KCl was studied by measuring changes in isometric tension in intact and diabetic animals. Initial contraction of aorta rings was markedly decreased in diabetic state. Secretin administered at two higher doses (10(-9), 10(-8) M) caused significa...

Analysis of phosphotyrosine and phosphoserine containing peptides by nano-electrospray Fourier transform ion cyclotron resonance (FTICR) mass spectrometry established electron capture dissociation (ECD) as a viable method for phosphopeptide sequencing. In general, ECD spectra of synthetic and native phosphopeptides appeared less complex than conventional collision activated dissociation (CAD) m...

Advanced Monte Carlo simulations are used to study the effect of nano-slit confinement on metric and topological properties of model DNA chains. We consider both linear and circularised chains with contour lengths in the 1.2–4.8 μm range and slits widths spanning continuously the 50–1250nm range. The metric scaling predicted by de Gennes’ blob model is shown to hold for both linear and circular...

Within the framework of the Landau-Lifshitz-Gilbert equation, using permalloy parameters, we study the statics and dynamics of flat circular magnetic nano-structures with an in-plane magnetic vortex configuration, putting particular emphasis on the vorticity of the magnetic state and on the (perpendicular) polarisation of the vortex center, which may be shifted with respect to the center of the...