Cystic hygromas are anomalies of the lymphatic system characterized by single or multiple cysts within soft tissue. The prenatal diagnosis of cystic hygroma by ultrasound is well documented in literature. Approximately 75-80% of all cystic hygromas involve the neck and the lower portion of the face, 15-20 % occur in the axilla , while remaining 5% are found in the mediastinum, retropertoneum,ab...

We report the prenatal diagnosis of cystic hygroma that was subsequently identified to have haploinsufficiency of the FOXF1 and FOXC2 genes via array comparative genomic hybridization (aCGH). Deletion o f these genes has previously neither been associated with cystic hygroma nor prenatally diagnosed. The FOX gene cluster is involved in cardiopulmonary development. This case expands the phenotyp...

L ymphangiomas (also called cystic hygroma, lymphactic or chylous cysts) are cystic abnormalities of the lymph vessels that are predominantly congenital, though acquired causes have been suggested. They typically present at birth or within the first 2 years of life. Most occur in the head and neck, occasionally the axilla or groin, and very rarely in the mediastinum. We report the case of a pat...