Objective: According to previous publications, the erratic hereditary disease with the augmented urinary excretion of cystine, could be envisage as the key to major injury in complicated patients due to recurrent of kidney stones. Therefore, the aim of this study was to investigate the safety and efficacy of Levisticum officinale (Lovage) in patients with cystinuria Patients and methods: Patien...

OBJECTIVE To report preliminary information on urinary stone composition in patients who are either overweight or obese with kidney stone disease. METHODS A cohort of patients (n = 138) with nephrolithiasis were prospectively followed from January 2011 for 18 months. Of those, 64 (46%) were found to be overweight with body mass index ≥ 25 kg/m(2) and 74 (54%) were obese with body mass index ≥...

OBJECTIVE Our aim was to determine, using CT attenuation values, the chemical composition of 241 human renal stones placed in a jelly phantom and to analyze the influence of respiratory motion on the classification. MATERIALS AND METHODS The stones were placed in a jelly simulating the X-ray attenuation of the kidneys. A dynamic platform was used to apply to the phantom free-breathing motion ...

Urolithiasis is the third most common disease of the urinary tract after infections and diseases of the prostate. Furthermore, there has been an increasing prevalence of calcium stones in the industrialized countries and between 5% and 15% of the population will develop kidney stones during their lifetime. Calcium stones (calcium oxalate or phosphate) compose the most common stone type. Other s...

Cystine stones occur in subjects carrying two autosomal mutant alleles resulting in excessive excretion of cystine, ornithine, arginine and lysine – hence the condition cystinuria. About 1:15–25 000 NSW neonates have been found to have cystinuria, with a gene frequency in Australia calculated to be about 1:4000 individuals. Since these studies were published, the mutant alleles have been identi...

Cystinuria (OMIM 220100) is an inborn congenital disorder characterised by a defective cystine metabolism resulting in the formation of cystine stones. Among the heterogeneous group of kidney stone diseases, cystinuria is the only disorder which is exclusively caused by gene mutations. So far, two genes responsible for cystinuria have been identified: SLC3A1 (chromosome 2p21) encodes the heavy ...