نتایج جستجو برای: cytopathy

تعداد نتایج: 86  

2015
Chia-Yu Chang Sheng-Mei Chen Huai-En Lu Syu-Ming Lai Ping-Shan Lai Po-Wen Shen Pei-Ying Chen Ching-I Shen Horng-Jyh Harn Shinn-Zong Lin Shiaw-Min Hwang Hong-Lin Su

Down syndrome (DS) patients with early-onset dementia share similar neurodegenerative features with Alzheimer's disease (AD). To recapitulate the AD cell model, DS induced pluripotent stem cells (DS-iPSCs), reprogrammed from mesenchymal stem cells in amniotic fluid, were directed toward a neuronal lineage. Neuroepithelial precursor cells with high purity and forebrain characteristics were robus...

2015
Roberto Sebastiá Ester Fallico Matteo Fallico Eduardo Fortuna Sergio Lessa Guilherme Herzog Neto

BACKGROUND The purpose of this work was to determine the effectiveness and possible complications encountered with bilateral fascia lata lid suspension used to correct blepharoptosis in patients with Kearns-Sayre syndrome. METHODS This was a retrospective study of seven patients with Kearns-Sayre syndrome who had a minimum of 1 year of follow-up. A bilateral fascia lata sling was used to corr...

2014
Sherezade Khambatta Douglas L Nguyen Thomas J Beckman Christopher M Wittich

BACKGROUND Kearns-Sayre syndrome (KSS) is a rare mitochondrial cytopathy, first described at Mayo Clinic in 1958. AIMS We aimed to define patient and disease characteristics in a large group of adult and pediatric patients with KSS. METHODS We retrospectively searched the Mayo Clinic medical index patient database for the records of patients with KSS between 1976 and 2009. The 35 patients i...

2016
Marco Marchionni Simone Caramel Sergio Stagnaro

The comprehension of the pathogenesis of epilepsy finds a new impulse in studies on non-linear dynamics of EEG signals and in the growing genetic molecular evidence of the mitochondrial origin of this disease. These data are consistent with the information known by Quantum Biophysical Semeiotics that clinically investigates microcirculation both on a functional (i.e. by studying its non-linear ...

2014
Jonna Nykky Matti Vuento Leona Gilbert

Proper functioning of the mitochondria is crucial for the survival of the cell. Viruses are able to interfere with mitochondrial functions as they infect the host cell. Parvoviruses are known to induce apoptosis in infected cells, but the role of the mitochondria in parvovirus induced cytopathy is only partially known. Here we demonstrate with confocal and electron microscopy that canine parvov...

2012
Prashanth Panduranga Kadhim Sulaiman

BACKGROUND Fahr's disease is a rare neurodegenerative disorder of unknown cause characterized by idiopathic basal ganglia calcification that is associated with neuropsychiatric and cognitive impairment. No case of Fahr's disease with associated cardiac conduction disease has been described in the literature to date. The objective of this case report was to describe a young female with various c...

Journal: :Blood 2013
Daniel H Wiseman Alison May Stephen Jolles Philip Connor Colin Powell Matthew M Heeney Patricia J Giardina Robert J Klaassen Pranesh Chakraborty Michael T Geraghty Nathalie Major-Cook Caroline Kannengiesser Isabelle Thuret Alexis A Thompson Laura Marques Stephen Hughes Denise K Bonney Sylvia S Bottomley Mark D Fleming Robert F Wynn

Congenital sideroblastic anemias (CSAs) are a heterogeneous group of inherited disorders identified by pathological erythroid precursors with perinuclear mitochondrial iron deposition in bone marrow. An international collaborative group of physicians and laboratory scientists collated clinical information on cases of CSA lacking known causative mutations, identifying a clinical subgroup of CSA ...

Journal: :Research in veterinary science 2013
Lilja Thorsteinsdóttir Einar G Torfason Sigurbjörg Torsteinsdóttir Vilhjálmur Svansson

The horse population in Iceland is a special breed, isolated from other equines for at least one thousand years. This provides an exceptional opportunity to investigate old and new pathogens in a genetically closed herd. Both types of equine gammaherpesviruses, EHV-2 and EHV-5, are common in Iceland. Genetic variation was examined by sequencing four genes, glycoprotein B (gB), glycoprotein H (g...

2013
Liucheng Ding Tao Song Chaoran Yi Yi Huang Wen Yu Lin Ling Yutian Dai Zhongqing Wei

The objective of this study was to investigate the effects and mechanism of Transcutaneous Electrical Nerve Stimulation (TENS) on the diabetic cytopathy (DCP) in the diabetic bladder. A total of 45 rats were randomly divided into diabetes mellitus (DM)/TENS group (n=15), DM group (n=15) and control group (n=15). The rats in the DM/TENS and TENS groups were electronically stimulated (stimulating...

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