introduction: astrocytes are the most abundant glial cell type. in addition to their neurological roles, astrocytes also have immune functions. they have been involved in antigen presentation in the central nervous system (cns). activated astrocytes express adhesion molecules, chemokines and release several inflammatory mediators, pro-inflammatory cytokines, neurotrophic and neuroprotective fac...

i n s u p p o r t i n g e n v i r o n m e n t a l s u s t a i n a b i l i t y, m a n a g i n g p r o d u c t r e t u r n s h a s b e c o m e a v e r y i m p o r t a n t a n d c h a l l e n g i n g i s s u e. r e s p o n d i n g t o t h i s t r e n d, r e s e a r c h e r s i n m a n y p a r t s o f t h e w o r l d h a v e c o n d u c t e d n u m e r o u s s t u d i e s i n r e v e r s e l o g i ...

new approach of breast cancer therapy is developed toward combination therapy with agent that have a specific molecular target. our previous study showed that citrus aurantifolia lime peels ethanolic extract (cpe) increased the sensitivity of mcf-7 cells againts doxorubicin. this study aims to observe the mechanism of combination cpe and doxorubicin in cell cycle modulation and apoptosis on mcf...

melissa (melissa offcinalis l.), a member of a lamiaceae family, is a medical plant. the main most important pharmacological properties can be soothin, strengthening nerve, carminative and memory booster. the presence of heavy metals is one of important environmental stresses that can reduce growth and production of types of reactive oxygen. in the present study, the effect of copper sulfate (c...

background: copper and zinc are the elements with numerous physiological activities.  copper  (cu)  has  an  important  role  in  angiogenesis  and  acts  by increasing vascular endothelial growth factor (vegf). serum levels of copper will be increased in cancer incidence, progression and recurrence. the aim of this study was to measure blood levels of copper, zinc, and the ratio of cu /zn, as ...

background phytotherapy is a popular treatment option in cases of benign prostatic hyperplasia (bph), with many different herbal products being used for the treatment of this condition. withania coagulans (wc) is an herbal medicine that has shown anti-tumoral, anti-inflammatory, and antioxidant effects. objectives this study examined the effect of withania coagulans extract (wce) on prostatic c...

urinary 1-hydroxypuren (1-ohp) is commonly used as a major metabolite and biological indicator of the overall exposure to polycyclic aromatic hydrocarbons (pahs). for evaluation of human exposure to such compounds, biological monitoring is an essential process, in which, preparation of samples is one of the most time-consuming and error-prone aspects prior to chromatographic techniques. in this...

characterization of isolated pigeon paramyxovirus-1 (pmv-1) and its pathogenicity in broiler chickens were studied. two hundred and thirty-two samples collected from 50 unvaccinated pigeons lofts suspected to newcastle disease from private houses and bird markets from ahvaz , iran. swab samples from cloaca and oropharynx of live pigeons and from trachea, lung, liver, spleen, kidney, brain, prov...

background & aim: eucalyptus l'her. [an aromatic genera of the family (myrtaceae)] is native to australia and other tropical species is planted worldwide. the purpose of this study is to extract and identify the essential oils components of four species of eucalyptus l'her. cultivated in botanical garden of kashan, central iran. experimental: leaves of e. largiflorens, e. intertexta, ...