AIMS Review the current evidence regarding the prevalence of methamphetamine use among men who have sex with men (MSM) and to evaluate the factors that contribute to methamphetamine use and potential for sexual transmission of HIV and other infectious diseases. METHODS Databased reports address (1) epidemiology of methamphetamine use in MSM; (2) methamphetamine use and risk behaviors for sexu...

Abstract Methamphetamine is a potent and highly addictive psychostimulant, one of the most widely used illicit drugs. Over recent years, its global usage seizure have been on rapid rise, with growing detrimental effects mental physical health, devastating psychosocial impact pressing for intervention. Among unwanted methamphetamine, acute long-term sleep impairments are major concern, posing si...

A previous study showed that cocaine self-administration induced dopamine-independent reinforcing effects of s agonists mediated by their selective actions at s1 receptors (s1Rs), which are intracellularly mobile chaperone proteins implicated in abuserelated effects of stimulants. The present study assessed whether the induction was specific to self-administration of cocaine. Rats were trained ...

Using Microgenics unique technology, cloned enzyme donor immunoassay (CEDIA), the multiplex assay (CEDIA Amphetamines/Ecstasy) has been developed for the detection of amphetamine, methamphetamine, and ecstasy drugs at cutoff level either of 500 ng/mL or 1000 ng/mL applicable for either qualitative screening or semiquantitative measurement. The multiplex assay detects the total concentration of ...

Nov 30, 2012 . Didrex is metabolized to methamphetamine. prescription drugs (Adderall and various amphetamine salts) or as a result of methamphetamine . Methamphetamine (contracted from Nmethylamphetamine) is a strong central nervous system. .. Methamphetamine is metabolized by the liver enzyme CYP2D6, so CYP2D6. .. Jump up to: "Adderall XR Prescribing Information" (PDF ). United . Nov 2, 2007 ...

Methamphetamine dependence has grown into an epidemic in the United States. An estimated 10.4 million people aged 12 years or older have tried methamphetamine.1 While the prevalence of methamphetamine use has remained constant in recent years, severity of use is increasing. The number of methamphetamine users in the past month meeting criteria for amphetamine abuse or dependence during the past...

Methamphetamine use among adolescents is a significant social and public health concern. Despite increased awareness of methamphetamine use among younger people, relatively little research has examined the effects of adolescent methamphetamine use compared to adult use. Thus, much remains to be learned about how methamphetamine alters adolescent brain function and behavior. In this article we r...

BACKGROUND AND PURPOSE Despite ample evidence supporting the N-methyl-D-aspartate receptor (NMDAR) hypofunction hypothesis of schizophrenia, progress in the development of effective therapeutics based on this hypothesis has been limited. Facilitation of NMDA receptor function by co-agonists (D-serine or glycine) only partially alleviates the symptoms in schizophrenia; other means to facilitate ...

BACKGROUND Methamphetamine is a major drug of abuse with no effective pharmacotherapy available. Trace amine associated receptor 1 is implicated in cocaine addiction and represents a potential therapeutic target. However, the effects of trace amine associated receptor 1 agonists on addiction-related behavioral effects of methamphetamine are unknown. METHODS This study examined the effects of ...